CLINICAL SUCCESS OF THE LIGHT-CURED CALCIUM SILICATE-BASED BIOMIMETIC MATERIAL FOR INDIRECT DENTAL PULP CAPPING AT SIX MONTHS

Main Article Content

Sultan Saeed Alqahtani
Mohammed Abdulrahman AlQahtani
Nasser Mohammed Almutairi
Yousef Saleh Alanazi
Mshari Suliman Al Mutairi
Nasser Tayeb Marir
Ali Alqahtani
Mohammed Saeed Alasiri
Turki Abdullah M AlQarni
Saeed Ateeq kh. Al Zahrani

Keywords

Biomimetic, Restorative dentistry, Indirect dental pulp capping, Meta-analysis

Abstract

Background: Biomimetic, bioinspired, and bioactive synthetic materials aim to replicate natural processes to address issues or substitute existing structures.


Aim: This meta-analysis study's primary goal was to investigate biomimetics in restorative dentistry.


Patients and Methods: The Cochrane Handbook for Systematic Reviews of Interventions and the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) criteria were both followed by this research. Based on the following PICO question components, the search strategy was created and executed utilizing the PubMed restricted vocabulary and free keywords. The Cochrane Risk of Bias Assessment Tool 1 (ROB1) was used to assess the quality of the included studies.


Results: No variations in clinical outcomes between the teeth treated using light-cured calcium silicate or other calcium-based materials were found in our meta-analysis of the clinical outcomes of indirect pulp capping in permanent teeth at six months. A statistically substantial variation favoring the control group was seen in our meta-analysis of the clinical effectiveness of indirect pulp capping in permanent teeth utilizing a light-cured calcium silicate-based material at 12 months.


Conclusion: There was no discernible variation between the controls and TheraCal LC in the available evidence for direct pulp capping in permanent teeth. After a year, indirect pulp capping in permanent teeth demonstrated a statistically significant variation that was in favor of the control group. Furthermore, since there was a chance of bias in the included research, the evidence's confidence ranged from low to moderate.

Abstract 316 | Pdf Downloads 59

References

1. Kottoor JO. Biomimetic endodontics: Barriers and strategies. Health Sci. 2013;2:7-12.
2. Chapple I, Gilbert AD. Quintessence Publishing. 2002 Jan 1.
3. SHAH, Deepa N. The Biomimetic Restorative Approach. Dental Update, 2021, 48.1: 13-20.‏
4. Srinivasan K, Chitra S. Emerging trends in oral health profession: the biomimetic-a review. Arch Dent Med Res. 2015;1(3):40-7.
5. Yang J, Yuan G, Chen Z. Pulp regeneration: current approaches and future challenges. Frontiers in physiology. 2016 Mar 7;7:58.
6. Giraud T, Jeanneau C, Rombouts C, Bakhtiar H, Laurent P, About I. Pulp capping materials modulate the balance between inflammation and regeneration. Dental Materials. 2019 Jan 1;35(1):24-35.
7. Cleymand F, Rousseau M, Mano JF. Introducing biomimetic approaches to materials development and product design for engineering students. Bioinspired, Biomimetic and Nanobiomaterials. 2015 Dec;4(4):207-12.
8. DA ROSA, Wellington LO, et al. C urrent trends and future perspectives of dental pulp capping materials: A systematic review. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2018, 106.3: 1358-1368.‏
9. Abou Neel EA, Roohpour N, Padidar B, Mordan NJ, Bozec L. Biomimetic dentin repair with a dual-analogue phosphate glass-polyacrylate paste: A proof-of-concept. Materials Chemistry and Physics. 2021 Jul 1;266:124539.
10. Bächli K, Schmidlin PR, Wegehaupt F, Paqué F, Ramenzoni L, Botter S. Remineralization of artificial dentin caries using dentin and enamel matrix proteins. Materials. 2019 Jul 1;12(13):2116.
11. Li X, De Munck J, Yoshihara K, Pedano M, Van Landuyt K, Chen Z, Van Meerbeek B. Re-mineralizing dentin using an experimental tricalcium silicate cement with biomimetic analogs. Dental Materials. 2017 May 1;33(5):505-13.
12. Wang T, Yang S, Wang L, Feng H. Use of multifunctional phosphorylated PAMAM dendrimers for dentin biomimetic remineralization and dentinal tubule occlusion. RSC Advances. 2015;5(15):11136-44.
13. Padovano JD, Ravindran S, Snee PT, Ramachandran A, Bedran-Russo AK, George A. DMP1-derived peptides promote remineralization of human dentin. Journal of Dental Research. 2015 Apr;94(4):608-14.
14. Liang K, Xiao S, Weir MD, Bao C, Liu H, Cheng L, Zhou X, Li J, Xu HH. Poly (amido amine) dendrimer and dental adhesive with calcium phosphate nanoparticles remineralized dentin in lactic acid. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2018 Aug;106(6):2414-24.