A COMPARATIVE STUDY OF INTRAOCULAR PRESSURE BETWEEN DIABETICS AND NON-DIABETICS IN A TERTIARY CARE HOSPITAL
Main Article Content
Keywords
Intraocular Pressure, Diabetics, Non-Diabetics.
Abstract
In this study, we wanted to compare IOP among diabetic population with that of an age-sex matched control population.
Methods
This was a hospital-based cross-sectional descriptive study conducted among patients who were randomly selected into diabetic group and non-diabetic group after taking detailed history, in the outpatient departments of Ophthalmology and Medicine in Burdwan Medical College & Hospital, Burdwan, West Bengal, for 18 months from June 2015 to May 2016 after obtaining clearance from the institutional ethics committee and written informed consent from the study participants.
Results
There were more number of people who were either current smokers or had a significant history of smoking in the past among the diabetic population in comparison to the control population and the difference was statistically significant. Similarly, the diabetic population were dyslipidemic in comparison to control group. The difference was statistically significant. The average central corneal thickness among the males in the diabetic population was 558.38±14.1 microns compared to 528.24±16.8 microns among those in the control group. The difference was extremely significant. Similarly, the average central corneal thickness amongst the females was higher in the diabetic population than in the non-diabetic population and the difference was extremely significant. In the same manner, the mean CCT adjusted IOP among the males was higher in the diabetic population as compared to non-diabetic population. The difference was highly significant. Among the females too similar findings were found. The mean CCT corrected IOP among the study population in the age group of 30-50 years, 50-70 years, and more than 70 years was 14.20±04 mmHg, 14.8±0.03 mmHg, 15.8±0.03 mmHg in comparison to 13.9±0.03 mmHg, 14.4±0.04 mmHg, 15.0±0.04 mmHg respectively in the control population. The difference in each age group was highly significant. The mean CCT adjusted IOP value among the patients with NPDR was 15.4±0.05 mm Hg and that among the patients with PDR the difference was extremely significant.
Conclusion
The CCT adjusted mean IOP level was significantly higher among the diabetic group as compared to the control population.
Keywords: Intraocular Pressure, Diabetics, Non-Diabetics.
References
2. Ellis J, Evans MM, Ruta D, Baines P, Leese G, MacDonald TM, et al. Glaucoma incidence in an unselected Cohort of diabetic patients: is diabetes mellitus a major risk factor for glaucoma. Br J Ophthalmol 2000;84(11):1218-24.
3. Pimentel LG, Gracitelli CP, da Silva LS, Souza AK, Prata TS. Association between glucose levels and intraocular pressure: Pre-and postprandial analysis in diabetic and nondiabetic patients. J Ophthalmol 2015;2015.
4. Ozdamar Y, Cankaya B, Ozalp S, Acaroglu G, Karakaya J, Ozkana SS. Is there a correlation between diabetes mellitus and central corneal thickness? J Glaucoma. 2010;19(9):613-6.
5. Venkatachalam J, Zile S, Sarguna D, Purty Anil J, Stalin P. Smoking and diabetes: a case control study in a rural area of Kancheepuram district of Tamil Nadu. IOSR Journal of Dental and Medical Sciences (JDMS) 2012;3(3):18-21.
6. Mathur A, Mathur R. Study of association of serum lipids with diabetic retinopathy in type 2 diabetes mellitus. People Journal of Scientific Research 2013;6 (1):25-8.
7. Abdelghaffar W, Ghobashy W, Abdo M, El-Baz A, Ibrahim M. Albuminuria as a biomarker for risk of retinopathy in type II diabetic patients in Suez Canal area. Egyptian Retina Journal 2013;1(2):18-22.
8. Pai S, Pai A, Ramasamy C, Kini R. A correlated study of BMI and IOP in diabetic and nondiabetic south population. Thai Journal of Physiological Sciences 2008;21(2):74-8.
9. Srikanth S, Susmitha A. A comparitive study of BMI and IOP in diabetic and nondiabetic population. Indian Journal of Basic & Applied Medical Research 2013;2(8):939-45.
10. Siddiqui F, Alkhairy S, Mazhar-ul-Hassan DK. Relationship between body mass index and intraocular pressure in diabetic and hypertensive adults. Pak J Ophthalmol 2016;32(1).
11. Abdulghani Y, Ali T. The correlation between central corneal thickness (CCT), and diabetes in Sudanese patients. National Journal of Medical Research 2013;3(4):309-11.
12. Mathebula SD, Segoati TM. Is the central corneal thickness of diabetic patients thicker than that of non-diabetics’ eyes? A Vision Eye Health 2015;74(1):5.
13. Baisakhiya S, Garg P, Singh S. The association between glycemic control and IOP in patients of Type II diabetes mellitus. National Journal of Physiology, Pharmacy and Pharmacology 2017;7(1).
14. Kaštelan S, Tomić M, Gverović Antunica A, Ljubić S, Salopek Rabatić J, Karabatić M. Body mass index: a risk factor for retinopathy in type 2 diabetic patients. Mediators of Inflammation 2013;2013:436329.
15. Hymowitz MB, Chang D, Feinberg EB, Roy S. Increased intraocular pressure and hyperglycemic level in diabetic patients. PLoS One 2016;11(3):e0151833.
16. Oshitari T, Fujimoto N, Hanawa K, Adachi-Usami E. Effect of chronic hyperglycemia on intraocular pressure in patients with diabetes. Am J Ophthalmol 2007;143(2):363-5.
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Dr. Arunanshu Dutta
Medical officer(specialist), Walsh SD Hospital, Serampore, Hooghly, West Bengal, India.
Dr. Purban Ganguly
Assistant Professor, Department of Ophthalmology, Regional Institute of Ophthalmology, Kolkata, West Bengal, India.
Dr. Asim Kumar Dey
Professor & HOD, Department of Ophthalmology. Gouri Devi Institute of Medical Sciences & Hospital, Rajbandh, Durgapur, West Bengal, India.
Dr. Indrajit Sarkar
Assistant Professor Department of Ophthalmology, Burdwan Medical College and Hospital, Burdwan, West Bengal, India.
Dr. Jayanta Biswas
Senior Resident and RMO cum Clinical Tutor, Department of Ophthalmology, MJN Medical College & Hospital, Coochbehar, West Bengal, India.