DRY EYE IN AUTOIMMUNE DISEASE (RHEUMATOID ARTHRITIS AND SYSTEMIC LUPUS ERYTHEMATOUS)
Main Article Content
Keywords
dry eye disease, autoimmune, rheumatoid arthritis, systemic lupus erythematosus
Abstract
Background: Autoimmune diseases are systemic disorders that involve many organs, including the eyes, and play an important role in dry eyes. This review aims to elucidate the relationship between dry eye disease (DED) and autoimmune disease.
Methods: This literature review utilized a database from 2020 until 2024. The keywords “dry eye disease”, “autoimmune", “rheumatoid arthritis", and “systemic lupus erythematous” were used to collect 9 journals that had relevant topics.
Results: Autoimmune diseases such as RA and SLE can cause DED through abnormal immune response mechanisms and inflammatory factors that harm the lacrimal glands, conjunctival membranes, corneas, and meibomian glands, resulting in tissue damage and dysfunction. This can lead to a decrease in the volume of tears and faster evaporation, resulting in DED.
Conclusion: This research shows a relationship between the incidence of DED and autoimmune diseases, including RA and SLE. Therefore, even in the absence of specific eye complaints, it is important to conduct examinations related to dry eyes in patients with autoimmune conditions.
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Diah Gemala Ibrahim
Department of Ophthalmology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
Hasnah B. Eka
Department of Ophthalmology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
Habibah S. Muhiddin
Department of Ophthalmology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
Ahmad Ashraf
Department of Ophthalmology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia