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Dr. Nitin Mehta
Dr. S. Banarjee.


Human Immunodeficiency virus (HIV), Immunosuppression, CD4 Cell, Serum Albumin


Background: HIV infection is still considered pandemic by the World Health Organization (WHO).  HIV infects the vital cells of the human immune system such as helper T cells (CD4+T cells), macrophages, and dendritic cells. When CD4+T cells decline below a critical level cell- mediated immunity will be lost, and hence the body progressively become more susceptible to all the opportunistic infections. This study was proposed among patient living with HIV to find out correlation between serum albumin and CD4 cell count as a marker of immunosuppression.

Material & Methods: This prospective study was conducted in Medicine Department, NIMS Hospital, Jaipur between July 1, 2022, to May 31, 2023, and included HIV patients of age 18 years and above living around Jaipur.

Results: Total 102 study subjects were enrolled in this study and majority belonged to age 31-40 years (52%) and 41-50 years (36%) with male predominance (58%) over female. Most of them were presented with fever, weakness and altered bowel habits. A strong positive correlation was found with statistically significant p values of < 0.0001 & <0.00001 respectively. There is linear trend in regression analysis.

Conclusion: This study concluded that there is a positive correlation between serum albumin and CD4 cell count among patient living with HIV. Serum albumin could be used as surrogate marker of immunosuppression in HIV/AIDS patients.

Abstract 41 | PDF Downloads 49


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