Clinical and Radiographic Evaluation of Low Level Laser Therapy on Implants' Osseointegration in Posterior Maxillary Edentulous Region in Postmenopausal Patients

Main Article Content

Hussein Adel Fathallah ; Amr Aly El-Swify ; Ahmed Abbas Zaky ; Ahmed El Rawdy


Postmenopausal Patients ; Osseointegration; Low Level Laser Therapy


The use of dental implants to compensate the loss of teeth has increased through the last 30 years. The aim of the present study was to evaluate Low Level Laser Therapy (LLLT) on Implants Osseointegration in Posterior Maxillary Edentulous Region in Postmenopausal Patients. Patients and methods: The study was inducted on sixteen implants on eight postmenopausal patients with age range 54-57 years. Patients were divided equally into control group consisted of 4 individuals who had 8 implants inserted, and study group consisted of 4 individuals who had 8 implants inserted followed by low-level laser therapy. All patients were evaluated by CBCT preoperatively and by digital radiograph 2 weeks after implant placement, 3 months and 6 months postoperatively. All implants were clinically evaluated for implant stability OSTELL device immediately after implant placement and 6 months postoperatively. Results: No clinical postoperative infection was observed in all cases. LLLT plays a good role as a pain killer and lowering the swelling possibility.There was a significant difference between the immediate and 6months in control (P<0.001) and laser (P=0.002) groups. . There was a highly significant difference between clinical and X-ray results in the control and laser groups at immediate and after 6 months. The mean values were high in the laser group compared with control group. Conclusion: The use of low level laser therapy with implants on maxillary posterior region on postmenopausal patients provides better implant stability and enhances osseointegration

Abstract 17 | PDF Downloads 11


1- Abraham, C. M., (2014). A brief historical perspective on dental implants, their surface coatings and treatments. The Open Dentistry Journal, 50(5), p. 8.
2- Crespi, R., Capparè, P., & Gherlone, E. (2010). Fresh-Socket Implants in Periapical Infected Sites in Humans.. Journal of Periodontology, 81(3), p. 378–383.
3- Jang, H.-W., Kang, J.-K., Lee, K., Lee, Y.-S., & Park, P.-K., (2011). A retrospective study on related factors affecting the survival rate of dental implants. . The Journal of Advanced Prosthodontics, 3(4), p. 204–215.
4- Pourzarandian A, Watanabe H, Ruwanpura SM, Aoki A, Ishikawa I , (2005). Effect of low level er:YAG laser irradiation on cultured human gingival fibroblasts. J Periodontol,76(187-93).
5- Bissinger O, et al., (2017). Comparative 3D micro-CT and 2D histomorphometry analysis of dental implant osseointegration in the maxilla of minipigs. J Clin Periodontol, 44(4), 418–27.
6- Da Silva RV, Camilli JA, (2006). Repair of bone defects treated with autogenous bone graft and low-power laser. J Craniofac Surg, Volume 17, p. 297-301.
7- Avci P, Gupta A, Sadasivam M, Vecchio D, Pam Z, Pam N, et al, (2013). Low level laser (light) therapy (LLLT) in skin: Stimulating, healing, restoring. Semin Cutan Med Surg, 32(41), p. 52.
8- Cremonini CC, Dumas M, Pannuti CM, et al, (2011). Assessment of linear measurements of bone for implant sites in the presence of metallic artefacts using cone beam computed tomography and multislice computed tomography. Int J Oral Maxillofac Surg, Volume 40, pp.845-850.
9- Gao J, Matsushita Y, Esaki D, Matsuzaki T, Koyano K. , (2014). Comparative stress analysis of delayed and immediate loading of a single implant in an edentulous maxilla model. J Dent Biomech, Volume 5, pp. 1-7.
10- Soleimani M, Abbasnia E, Fathi M, Sahraei H, Fathi Y, Kaka G, (2012). The effects of low-level laser irradiation on differentiation and proliferation of human bone marrow mesenchymal stem cells into neurons and osteoblasts—an in vitro study. Lasers Med Sci, 27(2).
11- Khadra, M., Lyngstadaas, S. P., Hans, R., Haanæs, H. R., Mustafa, K, (2005). Effect of laser therapy on attachment, proliferation and differentiation of human osteoblast-like cells cultured on titanium implant material.. Biomaterials, Volume 26; 3503–3509.
12- Mayer L, Gomes FV, Carlsson L, Gerhardt-Oliveira M, ( 2015). Histologic and resonance frequency analysis of peri-implant bone healing after low-level laser therapy: an in vivo study. Int J Oral Maxillofac Implants., 30(5);1028-35.
13- Radwan, D. A., (2005). A clinical study on the effect of diode laser therapy on the osseointegration of delayed immediate implants.. A thesis of doctor’s degree in oral surgery, Cairo University.
14- Mandić B, Lazić Z, Marković A, Mandić B, Mandić M, Đinić A, et al, (2015). Influence of postoperative low-level laser therapy on the osseointegration of self-tapping implants in the posterior maxilla: a 6-week split-mouth clinical study. Vojnosanit Pregl, 72(3);233–40.
15- Renno, A. C. M., Gomes, A. R. S., Nascimento, R. B., Salvini, T., & Parizoto, N. (2007). Effects of a progressive loading exercise program on the bone and skeletal muscle properties of female osteopenic rats. Experimental gerontology, 42(6), 517-522.‏
16- Pretel H, Lizarelli RF, Ramalho LT, (2007) . Effect of low level laser therapy on bone repair: Histological study in rats. Lasers Surg Med, Volume 39;788-96.
17- Fávaro Pípi E, Feitosa SM, Ribeiro DA, Bossini P, Oliveira P, Parizotto NA, et al, (2010) . Comparative study of the effects of low intensity pulsed ultrasound and low level laser therapy on bone defects in tibias of rats. Lasers Med Sci, Volume ;25,727-32.
18- Garcia-Morales JM, Tortamano-Neto P, Todescan FF, de Andrade JC Jr., Marotti J, Zezell DM , (2012). Stability of dental implants after irradiation with an 830-nm low-level laser: a double-blind randomized clinical study.. Lasers Med Sci, 27(4), p. 703–711.
19- Matys J, Świder K, Grzech-Leśniak K, Dominiak M, Romeo U, (2019). Photobiomodulation by a 635 nm diode laser on peri-implant bone: primary and secondary stability and bone density analysis – a randomized clinical trial. BioMed Res Int, Volume 22, p. 164–171.
20- Torkzaban P, Kasraei S, Torabi S, Farhadian M., ( 2018) . Low-level laser therapy with 940 nm diode laser on stability of dental implants: a randomized controlled clinical trial. LasersMed Sci, 33(2), p. 287–93.
21- Gokmenoglu, C., Ozmeric, N., Erguder, I., & Elgun, S. (2014). The effect of light-emitting diode photobiomodulation on implant stability and biochemical markers in peri-implant crevicular fluid. Photomedicine and laser surgery, 32(3), 138-145.‏