A STUDY TO COMPARE THE EFFECT OF PRE-OPERATIVE SINGLE DOSE ANTIBIOTIC PROPHYLAXIS AND CONVENTIONAL ANTIBIOTIC COVERAGE IN CLEAN AND ELECTIVE SURGERIES

K.Praveen kumar; Karimaddela Keerthinmayee; Madhusudhan Varla; Gollapalli Kavitha; Ketha Balaji; Challapalli Srikanth Reddy; Gostu Chandra Sekhar

doi:10.53555/jptcp.v31i1.4245

K.Praveen kumar
Karimaddela Keerthinmayee
Madhusudhan Varla
Gollapalli Kavitha
Ketha Balaji
Challapalli Srikanth Reddy
Gostu Chandra Sekhar

Keywords

Surgical site infection, pre operative antibiotic prophylaxis, wound healing

Abstract

Background: The objective of the study was to compare the effectiveness of pre operative single dose antibiotic prophylaxis and conventional antibiotic coverage in clean and elective surgeries. Surgical site infection is defined as the development of microorganisms in a surgical incision site within the skin and subcutaneous fat, musculo-fascial layers or an organ or cavity. Surgical site infection is a common health care associated infection that causes significant postoperative morbidity and mortality. This study aims to compare the effectiveness of single dose pre operative antibiotic prophylaxis to prevent surgical site infections in suitable surgical patients in the interest of promoting cost effective surgical practice as well as reducing the development of bacterial resistance to antimicrobial agents.

Methods: This comparative prospective study was conducted on 100 individuals admitted to SVRRGGH, TIRUPATI, with the diagnosis requiring clean elective surgeries like inguinal hernia (all types undergoing mesh repair), hemi/total thyroidectomy and others for a period of one year . They were divided into 2 groups .Group A (receive single dose of inj.ceftriaxone 1gm just before skin incision) and Group B (receive post operative inj Ceftriaxone for 5 days. In this study, the surgical site infections is assessed following surgery.

Results: The occurrence of surgical site infection is comparatively less in the study group (those who received pre operative antibiotic prophylaxis) than that of the control group (multiple dosing of post operative antibiotic treatment).

CONCLUSION: The effectiveness of pre operative antibiotic prophylaxis is more than multiple post operative antibiotic treatment in preventing surgical site infection.

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Published

Jan 30, 2024

DOI https://doi.org/10.53555/jptcp.v31i1.4245

How to Cite

K.Praveen kumar, Karimaddela Keerthinmayee, Madhusudhan Varla, Gollapalli Kavitha, Ketha Balaji, Challapalli Srikanth Reddy, & Gostu Chandra Sekhar. (2024). A STUDY TO COMPARE THE EFFECT OF PRE-OPERATIVE SINGLE DOSE ANTIBIOTIC PROPHYLAXIS AND CONVENTIONAL ANTIBIOTIC COVERAGE IN CLEAN AND ELECTIVE SURGERIES. Journal of Population Therapeutics and Clinical Pharmacology, 31(1), 1720–1727. https://doi.org/10.53555/jptcp.v31i1.4245

Issue

Vol. 31 No. 1 (2024): JPTCP

Section

Articles

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