TO COMPARE THE NEW SMART & HANDY DEVICE DEVELOPED WITH STANDARD COLPOSCOPY FOR PRECANCEROUS &CANCER CERVIX SCREENING

Main Article Content

Professor N. Hephzibah Kirubamani

Keywords

Cancer cervical Screening, Low resources settings, Smart and handy devices, colposcopy

Abstract

Introduction: It is estimated that cervical cancer will occur in approximately 1 in 53 Indian women during their lifetime. Several screening options are available. Patients with abnormal screening tests are evaluated by colposcopy. The existing Colposcope instrument for cancer cervix has an LED light source and it requires a power supply to display images captured and requires a separate monitor. It is may not portable in most centers. This needs to have a working distance of 300 mm. The New   Smart and Handy device found to be easy to handle for cancer cervix screening and also cost-effective.  The USB camera in the device of the present invention captures pictures and video from a distance of 3cm to 4cm with good quality and clarity.


Aim objectives of the research project: To compare the images of a standard Colposcope with those of images of a Smart and handy device to detect precancerous and cancer cervix.


Objectives of the research project:



  • To determine whether smart and handy device can be utilized in low-resource centers to detect cancer cervix

  • To determine whether the quality of images captured is comparable with standard Colposcope

  • To determine the sensitivity & specificity of the smart and handy device diagnosis with that of standard Colposcope


Methodology & Research design: After informed, after ethical clearance 154   Women attending the Gynaec outpatient department were screened for detection of precancerous and cancerous lesions of the cervix using a standard Colposcope and with a Smart& Handy device. Inclusion criteria were women for routine cancer cervix screening, women with abnormal Pap test, women with white discharge, and women with postcoital bleeding and exclusion criteria were women with cervical growth.


Results: Focus of the image at 91%, Sharpness of the image at 92% and zoom at 94% with a Smart & handy instrument and by colposcope Focus -at 94%, sharpness at 98% and Zoom at 100% In Smart & hand   device evaluation done with Swede score   without vessels Based on   Aceto-white uptake, Margins, Lesion size, and Iodine uptake. Each was given two. score. Among -0 -3 score   - 53.3%, 4-5   score   -33.3%, 5-8 score   - 13.3% In Colposcopy evaluation done with Swede score based on Aceto-white uptake, Margins, Lesion size, Iodine uptake,5. Vessels, Among 0-3 score -60% 4-7 score- 26.6 %.8-10score   -13.4% Biopsy reports results in SMART AND HANDY DEVICE when score 0 -3   -Normal   -72%, Score of 4-5 – LSIL   - 15.8%, Score of 5-8-  - HSIL-6.2% COLPOSCOPY biopsy results when score of 0-4 –Normal-78%, Score of 5-7 – LSIL- 14.8%, Score of 8-10-HSIL -7.2%. The sensitivity, Specificity, Positive likelihood Ratio, and Negative Likelihood Ratio of Smart and hand Device are as follows 93.10%,90.32%,9.62, 0.08.


The sensitivity, Specificity, Positive likelihood Ratio, and Negative Likelihood Ratio   of colposcopy are as follows 96.55 % 93.33%, 14.48, 0.04


Conclusion: SMART AND HANDY DEVICE gives high-quality images and video and an efficient method to store data.  This can be incorporated into cervical screening methods in low-setting resources.

Abstract 47 | pdf Downloads 33

References

1. Ferlay J, Soerjomataram I, Ervik M, Forman D, Bray F, Dixit R, et al. GLOBOCAN 2012, Cancer Incidence and Mortality Worldwide in 2012. Lyon, France: International Agency for Research on Cancer; 2012. [Google Scholar]
2. Institute for Health Metrics and Evaluation. The Challenge Ahead: Progress and setbacks in breast and cervical cancer. Seattle, WA: IHME; 2011. [Google Scholar]
3. 3 Murthy NS, Juneja A, Sehgal A, Prabhakar AK, Luthra UK. Cancer projection by the turn of the century -Indian science. Indian J Cancer 1990;27:74-82.
4. Shastri SS, Dinshaw K, Amin G, Goswami S, Patil S, Chinoy R, et al. Concurrent evaluation of visual, cytological and HPV testing as screening methods for the early detection of cervical neoplasia in Mumbai, India. Bull World Health Organ 2005;83:186-94
5. Sankaranarayanan R, Nessa A, Esmy PO, Dangou JM. Visual inspection methods for cervical cancer prevention. Best Pract Res Clin Obstet Gynaecol. 2012;26:221–32. [Abstract] [Google Scholar]
6. Singh V, Parashari A, Gupta S, Sodhani P, Sehgal A.J : Performance of a low-cost magnifying device, Magnivisualizer, versus colposcope for detection of pre-cancer and cancerous lesions of the uterine cervix. Gynecol Oncol. 2014 Oct;25(4):282-6. doi: 10.3802/jgo.2014.25.4.282. Epub 2014 Jun 18.PMID: 25142620
7. Rashmi Bagga, Vanita Suri, Radhika Srinivasan, Niranjana Khandelwal, Payal Keswarpu, Sarif Kumar Naik Vidya Chandrasekhar, Lovi Gupta, Soubhik Paul, Feasibility of Using Mobile Smartphone Camera as an Imaging Device for Screening of Cervical Cancer in a Low-resource Setting; Journal of Postgraduate Medicine, Education and Research, April-June 2016;50(2):69-74
8. Emma R. Allanson, 1; Natacha Phoolcharoen,; Mila P. Salcedo,; Bryan Fellman, and Kathleen M. Schmeler,, Accuracy of Smartphone Images of the Cervix After Acetic Acid Application for Diagnosing Cervical Intraepithelial Neoplasia Grade 2 or Greater in Women With Positive Cervical Screening: A Systematic Review and Meta-Analysis: JCO Global Oncol 7:1711-1721. © 2021 by American Society of Clinical Oncology.
9. Rosa Catarino , Pierre Vassilakos, Stefano Scaringella , Manuela Undurraga ,Malinverno , Ulrike Meyer-Hamme , Dominique Ricard-Gauthier1 , Juan Carlos Matute1 , Patrick Petignat: Smartphone Use for Cervical Cancer Screening in Low-Resource Countries: A Pilot Study Conducted in Madagascar PLOS ONE | DOI:10.1371/journal.pone.0134309 July 29, 2015
10. Denisse Champin, Max carols Ramirez, and Javier Vargas Herrera, Ruud L. M. Bekkers,: Use of Smartphones for the Detection of Uterine Cervical Cancer: A Systematic Review: Cancers (Basal) 2021 Dec: 13(23) : 6047