EVALUATION OF PREDICTORS OF ARRHYTHMIA IN HYPERTROPHIC CARDIOMYOPATHY PATIENTS
Main Article Content
Keywords
HCM, ventricular arrhythmia, ICD
Abstract
Introduction: Hypertrophic cardiomyopathy (HCM) is a condition in which part of the heart becomes thick (hypertrophy) for no apparent reason. Ventricular (fibrillation and ventricular tachycardia) and supraventricular (AF) arrhythmias are common in these patients. This study was performed to evaluate and evaluate the electrocardiographic and echocardiographic factors associated with arrhythmia in HCM patients referred to the Rajaei Heart Center undergoing ICD implantation in patients with sudden arrhythmia (SCD), stroke, and exacerbation of heart failure. Taken is designed.
Materials and Methods: The present study is a descriptive-analytical study that was performed on patients of Rajaei Heart Center with the diagnosis of HCM for whom a cardiac device was implanted. The variables studied in this study included age, sex, type of clinical manifestation of HCM, family history of sudden death, patient's underlying electrocardiographic findings, recorded patient arrhythmias, patient echocardiographic findings, and type and number of patient ICD treatments including shock and ATP. Finally, the data were entered into SPSS software and analyzed. A significance level of 5% was considered for all analyzes.
Results: In the present study, out of 116 patients, 62 were male and 54 were female. The age range of patients was 20 to 87 years and the mean age of patients was 50.4 14 14 years. In the present study, there was a significant relationship between atrial fibrillation and mean ventricular thickness (P = 0.007) and left ventricular size (P = 0.04). In addition, there was no significant relationship between EF and ventricular arrhythmia (P = 0.57) but there was a significant relationship between EF and atrial fibrillation (P = 0.02).
Conclusion: In the present study, no factor was found that could significantly predict ventricular and supraventricular arrhythmias. In contrast, ventricular arrhythmias may be more common at older ages, with greater LV size, lower EF, and the presence of large, deep inverted TS.
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Alireza Saegh
School of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Seyedehsepideh Ghadirnezhadshiadeh
School of Pharmacy, Charles University, Prague, Czech Republic
Bahare Kasaei
School of Pharmacy, Azad University of Medical Sciences, Tehran, Iran
Melina Barahouei Moghaddam
School of Pharmacy, Yeditepe University, Istanbul, Turkey
Elaheh Mearaji
School of Pharmacy, O.O Bogomolets National Medical University, Kyiv, Ukrain
Mahdi Azadmanesh
School of Pharmacy, Azad University of Medical Sciences, Tehran Branch, Iran
Asma Hatami
Medical Chemistry Department, Faculty of Chemistry, University of Isfahan, Isfahan, Iran
Noushin Mashatan
Graduated, School of Applied Sciences, University of Brighton, Brighton, UK
Morteza Pishdadian
School of pharmacy, University of Bologna, Bologna, Italy
Ali Maleki
School of pharmacy, University of Bologna, Bologna, Italy
Mohammad Motazed Keivani
Student General Medicine, Sechenov First Moscow State Medical University, Moscow, Russia.
Seyed Abbas Pakmehr
School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Mahdi Zarei
Student Research Comittee, Tabriz University of Medical Sciences, Tabriz, Iran