EVALUATING THE THERAPEUTIC EFFICACY OF MORINGA OLEIFERA EXTRACT ON ALLOXAN-INDUCED DIABETIC RATS: A COMPARATIVE STUDY
Main Article Content
Keywords
Diabetes Mellitus, Moringa Oleifera, Blood Glucose, Glycated Hemoglobin
Abstract
Introduction
The current study is aimed to determine the effects of three different dosages that is 100, 200 and 300mg/kg of moringa leaves extract on blood glucose levels of alloxan induced diabetic as a potential treatment strategy in the treatment of DM
Methodology
A comparative experimental study was conducted on n=100 young Wistar rats divided into five groups. Laboratory condition was maintained at temperature of 20 to 250C and were exposed to 12 hours of light and 12 hours of dark cycle.
Results
Between the group Analysis were performed that provided significant evidence in favor of group D in comparison to other experimental groups where the values of HbA1C were significantly lowered p< 0.05 than values in group D and group E
Conclusion
The study had concluded that MO leaves extract had a therapeutic effects in managing high blood glucose levels in diabetes patients.
References
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Dr Muhammad Atif Ata
MBBS, M. Phil, Ph.D. Scholar, Institute of Biochemistry, University of Sindh,
Prof. Dr. Naseem Aslam channa
Chairperson, Institute of Biochemistry, University of Sindh
Dr Umair Ali Soomro
MBBS, M. Phil, Associate Professor, Department of Hematology, Indus Medical College, Tando Muhammad Khan, Sindh, Pakistan
Dr Kashif Rasheed Shaikh
MBBS, M. Phil, Ph. D Scholar, Professor, Department of Pharmacology, Suleman Roshan Medical College, Tando Adam, Sindh, Pakistan