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Dr Abdul Razzaque Nohri
Lilliam Lafont
Dr Alvin Llanos
Dr Hina Qasim


Dr Skin BEAUTY™ Wild Yam Hormonal Salve, Menopause, Wild yam


Background: Menopause is a natural process characterized by a reduction in certain gonadal hormones in females in their 40s. A lot of changes can be seen as the symptoms of menopause, such as those related to the central nervous system, metabolic changes, and weight gain, changes in cardiovascular health, urogenital and skin problems, and sexual dysfunction. Transdermal mode of delivery provides a practical and less risky alternative to oral consumption of drugs and also aims to serve as a better alternative to hypodermic injection. Topical Wild yam releases diosgenin, a precursor of gonadal hormone for managing menopausal symptoms and balancing hormones.

Methods: A cohort study was done on females of age 40-49 years, who were experiencing menopausal symptoms. The observation of a group of 34 females was done over time of 21 days (three weeks-three follow-ups) on Dr Skin BEAUTY™ Wild Yam Hormonal Salve followed by placebo effect (14 days) to assess the impact of intervention. A purposive non-probability sampling technique was used to collect the data on designed questionnaire, to test the effectiveness of a natural balm, Dr Skin BEAUTY™ Wild Yam Hormonal Salve. An informed consent was taken from every participant before intervention.

Results: Throughout the three subsequent evaluations, there was a persistent pattern of escalating beneficial outcomes observed with extended utilization of the hormonal salve, Dr Skin BEAUTY™ Wild Yam Hormonal Salve.  Most individuals did not encounter any adverse effects, which reinforces the salve's safety profile. The occurrence of night sweats showed a consistent improvement, reaching a relief rate of 82.3% after duration of three weeks. At the start, vaginal dryness was a common problem for 85.2% of participants. However, after 21 days, there was a significant improvement, with 73.5% of participants reporting alleviation. The study consistently showed a good trend in both sleep disturbances and mood disturbances, with a sustained improvement of 76.5% recorded at the final follow-up. The decrease in sexual desire elicited diverse reactions, with a significant rise in the number of individuals (47.1%) expressing positive changes after a period of 21 days. Considerable alleviation of symptoms such as hot flashes, and joint/muscle discomfort was seen, underscoring the importance of ongoing monitoring. Significantly, the issue of weight increase, which was a concern for 11.8% of participants at the beginning, showed no change till last follow-up with the salve.

Conclusion: The study explores the potential effectiveness of Dr Skin BEAUTY™ Wild Yam Hormonal Salve in reducing various postmenopausal symptoms over three weeks of treatment. Nonetheless, the variability in individual reactions underscores the complex nature of symptom management, emphasizing the need for personalized solutions and emphasizing the need for future research to gather a more precise understanding and establish customized treatment plans.

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1. Hess R, Thurston RC, Hays RD, Chang CCH, Dillon SN, Ness RB, et al. The impact of menopause on health-related quality of life: results from the STRIDE longitudinal study. Qual Life Res. 2012;21:535–44.
2. Monteleone P, Mascagni G, Giannini A, Genazzani AR, Simoncini T. Symptoms of menopause — global prevalence, physiology and implications. Nat Rev Endocrinol. 2018 Apr;14(4):199–215.
3. Shifren JL, Crandall CJ, Manson JE. Menopausal hormone therapy. Jama. 2019;321(24):2458–9.
4. Flores VA, Pal L, Manson JE. Hormone therapy in menopause: concepts, controversies, and approach to treatment. Endocr Rev. 2021;42(6):720–52.
5. Prausnitz MR, Langer R. Transdermal drug delivery. Nat Biotechnol. 2008;26(11):1261–8.
6. Dantas SM. Menopausal symptoms and alternative medicine. Prim Care Update OBGYNS. 1999;6(6):212–20.
7. Oladebeye AO, Oladebeye AA, Arawande JO. Physicochemical Properties of Wild Yam (Dioscorea villosa) Starch. Hashemi Gahruie H, editor. Int J Food Sci. 2023 Sep 29;2023:8868218.
8. Sadhan M. Anticancer Potential of Biologically Active Diosgenin and its Derivatives: An Update. Current Traditional Medicine. 2024;10(1):67-80(14).
9. Park MK, Kwon HY, Ahn WS, Bae S, Rhyu MR, Lee Y. Estrogen activities and the cellular effects of natural progesterone from wild yam extract in mcf-7 human breast cancer cells. Am J Chin Med. 2009;37(01):159–67.
10. Wu WH, Liu LY, Chung CJ, Jou HJ, Wang TA. Estrogenic effect of yam ingestion in healthy postmenopausal women. J Am Coll Nutr. 2005;24(4):235–43.
11. Glazier MG, Bowman MA. A review of the evidence for the use of phytoestrogens as a replacement for traditional estrogen replacement therapy. Arch Intern Med. 2001 May 14;161(9):1161–72.
12. Komesaroff PA, Black CVS, Cable V, Sudhir K. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001;4(2):144–50.
13. Shayan A, Masoumi SZ, Soltani F, Niyatabesh RA, Moradkhani S, Farhadian M, et al. Comparing the Effect of Cimifugol and Salvigol on Night Sweats in Postmenopausal Women: A Single-blind Clinical Trial. J Midwifery Reprod Health. 2020;8(4).
14. OJIMELUKWE P, Muoasinam C, Omodamiro R. Current perspectives on the Nutrient composition and health benefits of yams (Discorea species). Int J Agric Environ Food Sci. 2021;5(2):179–90.
15. Hsu CC, Kuo HC, Chang SY, Wu TC, Huang KE. The assessment of efficacy of Diascorea alata for menopausal symptom treatment in Taiwanese women. Climacteric. 2011;14(1):132–9.
16. Shou C, Li J, Liu Z. Complementary and alternative medicine in the treatment of menopausal symptoms. Chin J Integr Med. 2011;17:883–8.
17. Haimov-Kochman R, Hochner-Celnikier D. Hot flashes revisited: Pharmacological and herbal options for hot flashes management. What does the evidence tell us? Acta Obstet Gynecol Scand. 2005;84(10):972–9.

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