REVEALING THE PHYTOCHEMISTRY, PHARMACOLOGY AND TOXICOLOGY OF ALLIUM SATIVUM -A REVIEW

Main Article Content

Anandarajagopal Kalusalingam
Roshan S

Keywords

Alliumsativum, garlic, review, phytochemistry, pharmacology, toxicology

Abstract

Allium sativum Linn, a member of the Amaryllidaceae family, commonly known as garlic, holds global significance as a herbal supplement. It is widely utilized for both the prevention and treatment of various diseases in different cultures. Garlic plays a prominent role in traditional medicinal systems, such as traditional Chinese medicine, Islamic medicine, folklore medicine, and the Indian Ayurvedic system, where it is recognized as an effective remedy for numerous human ailments. The objective of this study was to examine scientific articles exploring the therapeutic potential of A. sativum, with the aim of providing up-to-date and reliable scientific evidence to support the use of garlic in promoting human health and managing various health issues.The information underscores the natural gift that garlic offers to humanity. Based on the comprehensive data discussed, A. sativum has the potential to serve as a treatment for a wide range of ailments by inhibiting various bacteria, fungi, harmful viruses, and insects. Garlic's manifold therapeutic properties, including its antioxidative capacity, antidiabetic, antihyperlipidemic, thrombolytic, cardioprotective, hepatoprotective, neuroprotective, and potential anticancer effects, make it an exceptional natural remedy for a variety of health concerns. These effects can be attributed to the diverse array of bioactive compounds found in garlic, including alkaloids, flavonoids, phenolic compounds, and organosulfur compounds like allicin and ajoene. However, it is also important to carefully examine potential adverse effects and safety considerations. Further research is crucial to gain a comprehensive understanding of the mechanisms underlying garlic's effects to validate its potential health benefits for humans.

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