Main Article Content

Ika Puspita
Marlyanti Nur Rahmah
Ratih Natasha Maharani
Rani Yunita Patong
Muhammad Irfan Kamaruddin


atropine, childhood myopia, efficacy, progressive myopia


Objective: This review was carried out to determine the efficient concentration of atropine eye drops in inhibiting the progression of myopia in children.

Materials & Methods: A literature search was conducted across databases such as PubMed, ScienceDirect, SpringerLink, and ProQuest, using search terms such as "myopia progression","myopia", and "atropine". The evaluation of efficacy was based on Corrected Visual Acuity, axial length, and adverse effects.

Results: The study included data from 12 Randomized Controlled Trials (RCTs) comprising3,651 participants exposed to seven atropine concentrations, including 1%, 0.5%, 0.1%, 0.05%, 0.02%, 0.025% and 0.01%. The results showed that higher atropine doses were more effective in slowing myopia progression.

Conclusion: Very Low Dose Atropine eye drops have proven to be sufficiently efficacious in decelerating the progression of myopia in pediatric patients, showing minimal side and rebound effects.

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