IMPACT OF PREGNANCY ON PHARMACOKINETICS OF MEDICATIONS

Main Article Content

Mary F Hebert

Keywords

Pharmacokinetics, pharmacodynamics, drug metabolism, cytochrome P450, drug clearance, drug disposition, physiological changes, pregnancy

Abstract

Pregnancy is associated with significant physiological changes that alter the pharmacokinetics and pharmacodynamics of medications during pregnancy. This overview describes the effects of pregnancy on kidney filtration, drug transport, drug metabolism, protein binding, and their clinical implications for drug therapy.

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References

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