Essential Oil Nanoemulsion Formulations, Characterization, and Study of its Antibacterial Activity Against Clinical Isolates of S. aureus

Main Article Content

Vaishali Pimple
Archana Kulkarni
Suvarna Patil
Seema Nimbarte

Keywords

Antibiotic resistance, Essential oils, Nanoemulsions

Abstract

From past few years bacterial resistance to antibiotics is posing the severe issue to healthcare sector. Therefore there is urge to find out natural antimicrobial agents. Essential oils are one of the promising option to deal with antibiotic resistance. But poor solubility, stability and odor makes its use restricted. These limitations can be avoided by using nanoemulsion formulations of essential oils. In present study, nanoemulsion formulations of Tea tree oil, Thyme oil, and Clove oil and Cinnamon oil were synthesized using probe ultrasonicator. Physicochemical characterization and stability studies were carried out and tested for droplet size and polydispersibilty index (pdi).Formulated nanoemulsions were tested against clinical isolates of S.aureus. The nanoemulsion formulations of Cinnamon oil demonstrated promising results.

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