PREVALENCE OF TRANSFUSION TRANSMISSIBLE DISEASES BETWEEN MADINAH BLOOD BANK DONORS, SAUDI ARABIA
Main Article Content
Keywords
Blood Bank, Blood Donor, Transfusion-Transmissible Diseases, serology
Abstract
Objective: The possible risk of TTD caused by blood-borne pathogens is one of the most undesirable risks of blood transfusion worldwide. This study aimed to screen TTD carriage and prevalence in Madinah blood bank donors and to describe the dominant TTD in the study area within Al-Madinah city. The study also aimed to provide an examination over time of the prevalence of TTDs for three years 2020, 2021 and 2022, at Al-Madinah blood banks and compare validated results obtained from previous studies with our study results.
Methods: The testing method included screening serological tests for TTDs and confirmation assays according to each pathogen. The samples were collected and tested according to guidelines approved by the AABB, CBAHI and Saudi FDA. The study subjects were 104538 male and female volunteers and replacement donors aged 18 to 60 years who donated blood from 2020 to 2022 at five blood banks within Al-Madinah city. Donor samples were tested, abnormal TTDs results were further tested for confirmation, and all results were documented according to the following policy.
Results: A total of 104538 donors, 1061 donors giving abnormal serology results for at least one marker, had an overall carriage rate of 1.01%, and only 416 were confirmed by the approved confirmation method. Out of 1061 serology-positive donors, 334, 305, 214, 105 and 103 donors were positive for HBV, HCV, syphilis, HIV and HTLV infection, respectively.
HBV was the dominant TTDs marker, with an incidence rate of 31.47%, over other positively screened TTDs.
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Riyad Ali Al-Ahmadi
Blood Banking and Transfusion Senior Specialist, Madinah Regional Blood Bank – Ministry of Health. Almadinah Almunwrah – Saudi Arabia
Alaa Assad Bukhari
King Salman Medical City - Ministry of Health. Almadinah Almunwrah – Saudi Arabia
Ahmed Mousa Alsharyfi
King Salman Medical City - Ministry of Health. Almadinah Almunwrah – Saudi Arabia
Fayez Hadhrm Alsihli
Madinah Regional Blood Bank – Ministry of Health. Almadinah Almunwrah – Saudi Arabia. Email
Sultan Abdulhadi Sanosi
King Salman Medical City - Ministry of Health. Almadinah Almunwrah – Saudi Arabia
Ahmed Adil Sahlool
Madinah Regional Blood Bank – Ministry of Health. Almadinah Almunwrah – Saudi Arabia.
Abdulrahman Alanizi
King Fahad Hospital - Ministry of Health. Almadinah Almunwrah – Saudi Arabia
Abdullah Barrak Almutairi
King Abdullah Medical City - Ministry of Health. Makkah – Saudi Arabia
Mohammad Ali Albalwi
Madinah Regional Blood Bank – Ministry of Health. Almadinah Almunwrah – Saudi Arabia.
Bandar AlAhmadi
King Fahad Hospital - Ministry of Health. Almadinah Almunwrah – Saudi Arabia
Bader Ali AlAhmadi
Ministry of Health. Almadinah Almunwrah – Saudi Arabia.