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Mehreen Shamim
Hafeez Mushtaq
Suwaiba Azim
Rekha Kumari
Amjid Saira


Depression, Migraine, adults


Background: The following characteristics differentiate migraines apart from other headache types: they usually last between 4 and 72 hours, have a pulsating nature, affect only one side of the head, are moderate to severe in intensity, and are made worse by physical activity. A multitude of factors, including genetics, hormones, the environment, food choices, sleep quality, and psychological elements, all play a distinct role in the development of migraine, making it a complex disorder. Depression is a psychological disease that is frequently experienced by those who have migraine headaches. Depression in migraineurs is thought to increase the likelihood of developing chronic migraines, decrease responsiveness to migraine therapies, lead to medication abuse, induce suicidal thoughts linked to psychological issues, and have a detrimental effect on migraineurs' general quality of life.

Objective: This study aimed to find out how common depression is among those who get migraines.

Study design: A cross-sectional study

Place and Duration This study was conducted in Usman Memorial Hospital Karachi from July 2022 to July 2023

Methodology: The patients involved in this research were those who had visited the clinic of neurology during the period of our research. Every patient in this research was diagnosed with a migraine and was on regular follow-up care. The patients were given the choice of answering a questionnaire on paper or online. SPSS version 26 was used to analyze the data. Every statistical technique used was a two-sided test, with a significance level of 0.05 being applied to determine significance (p-values less than or equal to 0.05).

Results: In this research, there were a total of 150 people selected as participants who were diagnosed with migraine. The age of the individuals was more than 18 years. The average age calculated was 36.9 years. Overall, 111 (74%) of the total participants were female. A total of 111 people were married, 30 were single, and 9 were divorced. A total of 89.3% of the participants indicated difficulty focusing on tasks; 84.6% expressed feelings of fatigue or low energy; 82% had diminished interest or enjoyment in activities; and 82% encountered issues with falling asleep, staying asleep, or experiencing excessive sleep.

Conclusion: The present study confirmed that migraine headaches are strongly linked to an increased prevalence of psychiatric disorders, particularly depression.

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