COMPARATIVE ANALYSIS OF MORPHOLOGICAL AND HISTOLOGICAL IMPACT ON THE RESPIRATORY TRACT OF ALBINO MICE EXPOSED TO ALLETHRIN-BASED VAPORIZER FUMES VS MOSQUITO COIL SMOKE

Abstract

Mosquito repellent products release chemical compounds into the atmosphere, leading to concerns regarding their potential impact on individuals who inhale these compounds during usage. In this study, the effects of allethrin exposure, a common ingredient in mosquito repellents such as coils and liquid vaporizers, were examined on the respiratory health of mice. The research assessed alterations in body weight. An animal experiment involved 42 mice in three groups: Control, Liquid Vaporizer, and Mosquito Coil. Their weights were measured at the beginning and end of an 8-week study. Trachea and bronchi, including lungs, were examined grossly. SPSS was used for analysis. The study revealed that exposure to liquid vaporizer and mosquito coil emissions led to changes in mice's body weight, lung color, texture, and the presence of eroded patches. These effects were most pronounced in the Mosquito Coil group, while the Control group remained unaffected. Statistical analysis confirmed the significance of these differences, emphasizing the potential harm of long-term insecticidal exposure. The evaluation of allethrin, a common mosquito repellent component, on respiratory health revealed significant adverse effects.