A PROSPECTIVE STUDY ON ISCHEMIC STROKE CAUSED DUE TO COMORBID CONDITIONS, USE OF LMWH AND ITS OUTCOME

Main Article Content

Dr. Aishwarya Dinakaran
Shaesta Maheen Fatima
Aleem Unnisa Begum Alias Fatika Begum
Mohammed Abdul Bari Ahmed
Misbah Zareen
Dr. Sudhakara Rao

Keywords

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Abstract

AIM:



  • The study aims to detect the effects of co-morbid conditions leading to ischemic stroke.

  • sage of LMWH and its outcomes in a tertiary care hospital.


OBJECTIVES:



  • To assess the risk among patients in ischemic stroke with co-morbid conditions.

  • To assess safety profile, and documented clinical outcomes, in patients prescribed with heparins suffering from Acute ischemic stroke.


MATERIALS AND METHOD: 


An observational study was accomplished on inpatients, who were confirmed ischemic stroke throughout 6 months. Patients on LMWH drug therapy were evaluated to know the outcomes and the co-morbid conditions leading to ischemic stroke. The data was collected and documented.


RESULT:


A total of 152 inpatients were observed according to their co-morbid conditions like CVA, DM, HTN, CAD, etc among which the prevalence of hypertension was majorly reported, followed by diabetes in concordance with the addictions like smoking and alcohol abuse, which may a reason for worsening of the condition.


Based on statistical analysis it is proven that comorbid condition indeed shows a significant affects on the progression of the disease by rejecting the null hypothesis.


CONCLUSION:


The patients suffered from co-morbid conditions such as diabetes and hypertension. In the following study 152 inpatients were observed. The collected data showed CVA, CAD and others among which the prevalence of hypertension was majorly reported and was followed by diabetes mellitus. Along with these comorbid conditions, the addictions like smoking and alcohol abuse played a vital role in worsening the stroke due to decreased oxygen supply.


Based on statistical analysis it is proven that comorbid condition indeed shows a significant affects on the progression of the condition by rejecting the null hypothesis. LOW MWH is a major drug used pharmacologically for the cure of TIA, and based upon the collected data it shows desirable outcomes in 99% of cases.


Among the 152 cases observed, its shows negative outcome in two cases by showing bleeding in patients. subjects with excessive blood loss are treated with TXA.

Abstract 79 | Pdf Downloads 22

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Published
Jun 23, 2023
DOI https://doi.org/10.53555/jptcp.v30i5.3203

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How to Cite
Dr. Aishwarya Dinakaran, Shaesta Maheen Fatima, Aleem Unnisa Begum Alias Fatika Begum, Mohammed Abdul Bari Ahmed, Misbah Zareen, & Dr. Sudhakara Rao. (2023). A PROSPECTIVE STUDY ON ISCHEMIC STROKE CAUSED DUE TO COMORBID CONDITIONS, USE OF LMWH AND ITS OUTCOME . Journal of Population Therapeutics and Clinical Pharmacology, 30(5), 766–776. https://doi.org/10.53555/jptcp.v30i5.3203
Issue
Vol. 30 No. 5 (2023)
Section
Articles
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Author Biographies

Dr. Aishwarya Dinakaran

Associate Professor, Department of Pharmacy Practice, MRM College of Pharmacy, Chintapally guda, Hyderabad-501510.

Shaesta Maheen Fatima

Department of Pharmacy Practice, MRM College of Pharmacy, Chintapally guda, Hyderabad501510.

Aleem Unnisa Begum Alias Fatika Begum

Department of Pharmacy Practice, MRM College of Pharmacy, Chintapally guda, Hyderabad501510.

Mohammed Abdul Bari Ahmed

Department of Pharmacy Practice, MRM College of Pharmacy, Chintapally guda, Hyderabad501510.

Misbah Zareen

Department of Pharmacy Practice, MRM College of Pharmacy, Chintapally guda, Hyderabad501510.

Dr. Sudhakara Rao

Professor and HOD, Department of Pharmacy Practice, MRM College of Pharmacy, Chintapally guda, Hyderabad-501510.