"PREDICTION OF RESPONSE TO CLINICAL TREATMENT IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA DIAGNOSED WITH PRONOUNCED MIDDLE LOBE"

Main Article Content

Pablo Andrés Alvarez Barros
Franklin Fernando Cisneros Espín

Keywords

Prostatic hyperplasia, pharmacological treatment, adrenergic alpha-Antagonists

Abstract

Benign Prostatic Hyperplasia (BPH) stands as the most prevalent noncancerous growth in the prostate gland in elderly men, characterized by the enlargement of the prostate gland. A subtype of BPH that has garnered the interest in the medical community is one in which a significant increase in the middle lobe is evident, which can lead to various complications and challenges in clinical management. Methodology: The study adopts a systematic approach to review the literature on treatment response in patients with benign prostatic hyperplasia and a notably affected middle lobe. A comprehensive search was conducted in medical and scientific databases using relevant keywords and temporal filters. Clinical studies that met specific inclusion criteria were selected, and bibliometric analysis was performed to identify prominent journals in this field and their impact. This provides a comprehensive view of research in this domain and its influence on the scientific community.


Result: Various non-invasive therapies, such as psychosexual therapy and phosphodiesterase 5 inhibitors (PDE5), have shown significant improvements in the symptoms of benign prostatic hyperplasia (BPH) without negatively affecting sexual function. Multiple surgical procedures, such as open prostatectomy, transurethral resection of the prostate (TURP), and arterial embolization of the prostate (AEP), are used in the treatment of BPH, each with different success rates and risks. GreenLight laser photoselective vaporization is an effective and safe option.


Conclusion: Risk factors, treatment selection, and the importance of early diagnosis are emphasized, along with the ongoing need to research and improve therapies for this common condition in older men.

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