PHYTOCHEMICAL AND PHARMACOLOGICAL REVIEW OF ETHNO MEDICINAL PLANT: JATROPHA CURCAS L.

Main Article Content

Dr. Nidhi Tyagi
Nitin Chaudhary

Keywords

Dermatomucosal, Jatropha curcas, Euphorbiaceae, Human immunodeficiency virus

Abstract

Jatropha curcas (Family:Euphorbiaceae); Physic nut a drought-resistant shrub or tree, which is widely distributed in the wild or semi-cultivated areas in Central and South America, Africa, India and South East Asia. Jatropha curcas is a drought resistant, perennial plant that grows even in the marginal and poor soil. Raising Jatropha is easy. It keeps producing seeds for many years. In the recent years, Jatropha has become famous primarily for the production of biodiesel; besides this it has several medicinal applications.The Jatropha curcas L. plant is used as a medicinal plant such as seeds against constipation; sap for wound healing; leaves as tea against malaria etc.Seeds used to treat arthritis, gout and jaundice.Stem acts in toothache, gum inflammation, gum bleeding, pyorrhoea.Plant extract used in treatment of allergies, burns, cuts and wounds, inflammation, leprosy, leucoderma, scabies and small pox.Water extract of branches is used in Human immunodeficiency virus, tumour and Plant extract in wound healing. Plant sap in dermatomucosal diseases

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References

1. Linnaeus C., Species plantarum. In: Jatropha. Impensis Laurentii Salvii, Stockholm, 1753; 1006–1007.
2. Cano-Asseleih L.M., Chemical investigation of Jatropha curcas L. seeds. Ph.D. Thesis. University of London. U.K., 1986.
3. Cano-Asseleih L.M., Plumbly R.A., Hylands P.J., Purification and partial characterization of the hem agglutination from seeds of Jatropha curcas. Jour. Food Biochem, 1989; 13: 1–20.
4. Heller J., Physic nut, Jatropha curcas L. Promoting the conservation and use of underutilized and neglected crops. Institute of Plant Genetics and Crop Plant Research, Gartersleben, International Plant Genetic Resources Institute, Rome. 1996; 1.
5. Cano-Asseleih L. M., Chemical investigation of Jatropha curcas L. seeds. Ph.D. Thesis. University of London U.K., 1986.
6. http://www.flickr.com/photos/jayjayc/471354992/
7. Gupta R.C., Pharmacognostic studies on ‘Dravanti’ Part I Jatropha curcas Linn. Proc. Indian Academic Science (Plant Science), 1985; 94: 65–82.
8. Staubmann R., Schubert-Zsilaveez M., Hiermannn A., Karting T., Phytochemistry, 1999; 50: 337-338.
9. Dehgan B., Webster G.L., Morphology and Intrageneric Relationships of the Genus Jatropha (Euphorbiaceae), University of California Publications in Botany. 1979; 74.
10. Ewurum G.A., Ugwoke C.E.C., Ezug wu., Pharmacognostic study of Jatropha curcas L. Journal of pharmaceutical and allied sciences, 2010; 7(3).
11. Li C., Dai Y., Wan D., Hu J., Wang J., Lijun T., Pharmacognostic and preliminary phytochemical investigation on Jatrophae curcatis Semen. Pharmacognosy Journal, 2(18): 210.
12. Singh R.P., Structure and development of seeds in Euphorbiaceae, Jatropha species. Beitr. Biol. Pflanz., 1970; 47: 79–90.
13. Hemalatha A., Radhakrishnaiah M., Chemosystematics of Jatropha. J. Econ. Taxonomical Bot, 1993; 17: 75–77.
14. Akintayo E.T., Characteristics and composition of Parkia biglobbossa and Jatropha curcas oils and cakes. Bioresour. Technol, 92; 307–310: 2004.
15. Augustus G.D.P.S., Jayabalan, M., Seiler, G.J., Evaluation and bio-induction of energy components of Jatropha curcas. Biomass Bioenergy, 2002; 23: 161–164.
16. Mitra C.R., Bhatnagar S.C., Sinha M.K., Chemical examination of Jatropha curcas. Ind. J. Chem, 1970; 8: 1047.
17. Khafagy S.M., Mohamed Y.A., Abdel N.A., Mahmoud Z.F., Phytochemical study of Jatropha curcas. Plant Med, 1977; 31: 274–277.
18. Hufford C.D., Oguntimein B.O., Non-polar constituents of Jatropha curcas. Lloydia, 1987; 41: 161–165.
19. Mishra S.B., Mukerjee A., VIjyaKumar M., Pharmacognostic and phytochemical evaluation of leaves extract of Jatropha curcas L. Pharmacognosy Journal, 2010; 2(15): 9-14.
20. Nath L.K., Dutta S.K., Acute toxicity studies and wound healing response of curcain, a proteolytic enzyme extract from the latex of Jatropha curcas L. In: Gubitz G.M., Mittelbach M., Trabi M. (Eds.), Biofuels and Industrial Products from Jatropha curcas. DBV Graz, 1997; 82–86.
21. Aregheore E.M., Makkar H.P.S., Becker K., Lectin activity in toxic and non-toxic varieties of J. curcas using a latex agglutination test. In: Gubitz G.M., Mittelbach M., Trabi M. (Eds.), Biofuels and Industrial Products from Jatropha curcas. DBV Graz, 1997; 65–69.
22. Duke J.A., CRC Handbook of Medicinal Herbs. CRC Press, Boca Raton, FL, 1988; 253–254.
23. Nwosu M.O., Okafor J.L., Preliminary studies of the antifungal activities of some medicinal plants against Basidiobol. 1995.
24. Tewari J.P., Shukla I.K., Inhibition of infectivity of two strains of watermelon mosaic virus by latex of some angiosperms. GEOBIOS, 1982; 9: 124–126.
25. Van den Berg A.J., Horsten S.F., Kettenes van den Bosch J.J., Kroes B.H., Beukelman C.J., Loeflang B.R., Labadie R.P., Curcacycline A: a novel cyclic octapeptide isolated from the latex of Jatropha curcas Linn. FEBS Lett, 358; 215–218: 1995.
26. Kaushik N., Kumar K., Kumar S., Kaushik N., Roy S., Genetic variability and divergence studies in seed traits and oil content of Jatropha (Jatropha curcas L.) accessions. Biomass Bioenergy, 31; 497–502: 2007.
27. Khare C.P., Indian medicinal plants. Springer Science+ Business Media, LLC. New Delhi, 2007; 126.
28. http://www.zipcodezoo.com/Plants/A/Aphanamixis_polystachya.asp.
29. Publication and Information Directorate. The Wealth of India, “Raw material”. New Delhi, 1992; 3:211.
30. Chopra R.N., Nayar S.L., Chopra I.C., Glossary of Indian medicinal plants. CSIR, New Delhi, 1999; 49.
31. Sawant H.P., Joshi Y.M., Kadam VJ., In vitroantioxidant activity in hydro-alcoholic extract of the leaves of Jatropha curcas Linn. Journal of Pharmacy Research, 2010; 3 (4): 2010.
32. Mishra S.B., Vijayakumar M., Ojha S.K., Verma A., Antidiabetic effect of Jatropha curcas L. leaves extract in normal and alloxan-induced diabetic rats. International general of pharmaceutical sciences, 2010; 2(1):482-487.
33. Donlaporn S, Suntornsuk W. Antifungal Activities of Ethanolic Extract from Jatropha curcas Seed Cake. J. Microbiol. Biotechnol. 2010; 20(2):319–324.
34. Gupta D. D., Haque E., Islam N., Mondal S.I., Shibib B.A., Antimicrobial and Cytotoxic activities of Jatropha curcas (Euphorbiaceae). Dhaka Univ. J. Pharm. Sci., 2010; 9(2): 139-142.
35. Sangeetha J., Divya K., Prashanth M.V., Vamsikrishna A., Leela rani G., Analgesic, anti-inflammatory and antibacterial activity of Jatropha curacs Linn. JPRHC,2010; 2(3):258-262.
36. Diwani G., Rafie S.Ei., Hawash S., Antioxidant activity of extracts obtained from residues of nodes leaves stem and root of Egyptian Jatropha curcas. African Journal of Pharmacy and Pharmacology, 2009; 3(11):521-530.
37. Balaji R., Suba V., Rekha N., Deecaraman M., Hepatoprotective activity of methanolic fraction of Jatropha curcas on aflatoxin b1 induced hepatic carcinoma. Int. J. Ph. Sci., 2009; 1(2):287-296.
38. Esimone C.O., Nworu C.S., Jackson C.L., Cutaneous wound healing activity of a herbal ointment containing the leaf extract of Jatropha curcas L. (Euphorbiaceae). International Journal of Applied Research in Natural Products, 2009; 1(4); 1-4.
39. Balaji R., Rekha N., Deecaraman M., Manikandan L., Antimetastatic and antiproliferative activity of methanolic fraction of Jatropha curcas against B16F10 melanoma induced lung metastasis in C57BL/6 mice. African Journal of Pharmacy and Pharmacology, 2009; 3(11):547-555.
40. Igbinosa O.O., Igbinosa E.O., Aiyegoro O.A., Antimicrobial activity and phytochemical screening of stem bark extracts from Jatropha curcas (Linn). African Journal of Pharmacy and Pharmacology, 2009; 3(2):58-62.
41. Wang J. C., Wu Y., Wang Q., Peng Y. L., Pan K.W., Luo ,P., Wu, N., Allelopathic effects of Jatropha curcas on marigold (Tagetes erecta L.). Allelopathy Journal, 2009; 24(1).
42. Kannappan N., Jaikumar S., Manavalan R., Muthu A.K., Antiulcer activity of methanolic extract of Jatropha curcas linn on aspirin induced gastric lesions in wistar rats. Pharmacologyonline newsletters, 2008; 1:279-293.
43. Ahirrao R.A., Pawar S.P., Borse L.B., Borse S.L., Desai S.G., Muthu A.K., Anthelmintic activity of leaves of Jatropha curcas linn and vitex negundo linn. Pharmacology online newsletters, 2008; 1: 279-293.
44. Yan R., Gao S., Yang W., Cao M., Wang S., Chen F., Nickel toxicity induced antioxidant enzyme and phenylalanine ammonia-lyase activities in Jatropha curcas L. cotyledons. Plant Soil Environ., 2008; 54(7): 294–30.
45. Oyi A.R., Onaolapo J.A., Haruna A.K., Morah C.O., Antimicrobial screening and stability studies of crude extract of Jatropha curcas Linn latex. Nig. Journ. Pharm. Sci., 2007; 6 (2): 14 – 20.
46. Shetty S., Udupa S.L., Udupa A.L., Vollala V.R., Wound healing activity of bark extract of Jatropha curcas L. in albino rats. Saudi Med J, 2006; 27(10):1473-1476.
47. Adebowale K.O., Adedire C.O, Chemical composition and insecticidal properties of the underutilized Jatropha curcas seed oil. African Journal of Biotechnology, 2006; 5 (10): 901-906.
48. Mujumdar A.M., Misar A.V., Anti-inflammatory activity of Jatropha curcas roots in mice and rats. Journal of Ethanopharmacology, 2004; 90(1):11-15.
49. Goonasekera M.M., Gunawardana V.K., Pregnancy terminating effect of Jatropha curcas in rats. Journalof Ethnopharmacology, 1995; 47(3):117-123.