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Shiv Jee Kashyap
Narendra Silawat


Imidazole, In-vitrooxidoreductase inhibitors, Anti-bacterial, Anti-infective agents.


Imidazole is an organic compound with the formula C3N2H4. It is a white or colourless solid that is soluble in water, producing a mildly alkaline solution. Imidazole is a highly polar compound, as evidenced by its electric dipole moment of 3.67 and is highly soluble in water. All the chemicals and glassware procured from our college, physicochemical characterization like melting point determination by open capillary method and TLC has been done according to solubility of compounds or derivatives in specific solvent alone or polarity ratio. Nine compoundshave been selected for synthesis and characterized by FTIR, NMR (1H, Proton analysis) Mass spectral analysis and further oxidoreductase inhibitorevaluation.Compound AP4 is also moderately active but less than the AP2, reason can be seen as AP4 is having a nitro group but also have electron acceptor group chlorine which is making it less potent than other only nitro substituted compounds.

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