FORMULATION AND EVALUATION OF ORAL MICROSPHERES CONTAINING ANTIHYPERTENSIVE DRUGS BY EMULSION SOLVENT EVAPORATION METHOD

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Akshay. M. Akotkar
Ashwini. A. Zanke
Kuldip V. Gite

Keywords

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Abstract

Hypertension is a serious heart condition in which the blood pressure in the arteries throughout the body is high. Blood pressure involves two measurements, systolic and diastolic. Normal blood pressure is equal to or less than 120/80 mmHg. High blood pressure is above 140/90 mmHg. The microspheres are thus spherical solid  particles with a size between 1 and 1000 μm.Using synthetic protein or polymer carbomer, ethyl cellulose, HPMC, ethanol, liquid paraffin, Span 80, etc. As raw materials, microspheres containing antihypertensive drugs were prepared by the emulsified solvent evaporation method.

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