PRESCRIBING PATTERNS OF ANTI HYPERTENSIVE DRUGS ON DIFFERENT COMPELLING INDICATIONS BASED ON JNC 8 GUIDELINES AND IMPACT OF LIFE STYLE MODIFICATIONS.

Main Article Content

Neelaphar P
Somasundaram I

Keywords

Hypertension, CKD patients, Myocardial infarction, stroke, DM

Abstract

Hypertension is becoming a global threat to the world population. Hypertension is one of the most common disorder and one of the most critical health problems causing multiple organ damage and death as single contributor in developed and developing countries. The aim of this study was to determine hypertension knowledge and practice in urban community in Karnataka. study was a cross sectional prospective observational questionnaire based, conducted among 750 hypertensive patients attending Department of General Medicine .RIMS, Andhra Pradesh, India All hypertensive patients with different co morbidities all either sex diagnosed with hypertension and aged above 18years old and exclusion Patients with recent Myocardial infarction or stroke Immediate post-operative patients and Those who are not willing to participate in this study Pregnant women and children are excluded. In this study AMLODIPINE is the mostly prescribed drug in HTN with CKD patients. NEBIVOLOL(26.34%) and METOPROLOL (12.20%) are the other drugs prescribed in HTN with CKD patients Prescribing Pattern of Antihypertensive drugs used for treatment in Tertiary Care Hospital, Bangalore and Karnataka was evaluated analyzed  and reported.

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References

1. Anchala R, Kannuri NK, Pant H, et al. Hypertension in India: a systematic review and meta-analysis of prevalence, awareness, and control of hypertension. J Hypertens. 2014;32(6):1170-1177. doi: 10.1097/HJH.0000000000000146. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
2. Chobanian AV, Bakris GL, Black HR, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7). Hypertension. 2003;42:1206-1252.
https://www.nhlbi.nih.gov/files/docs/guidelines/jnc7full.pdf. Accessed August 22, 2017. [PubMed] [Google Scholar]
3. James PA, Oparil S, Carter BL, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA. 2014;311(5):507-520. doi: 10.1001/jama.2013.284427. [PubMed] [CrossRef] [Google Scholar]
4. Government of India, Ministry of Health & Family Welfare. National List of Essential Medicines. Published 2011. http://pharmaceuticals.gov.in/pdf/NLEM.pdf. Accessed on August 23, 2017.
5. Sepehri G, Talebizadeh N, Mirzazadeh A, Mohsenbeigi M. The patterns of antihypertensive drug prescription by cardiologists in Kerman province of Iran, 2006. Pharmacoepidemiol Drug Saf. 2008;17(2):180-185. doi: 10.1002/pds.1521. [PubMed] [CrossRef] [Google Scholar]
6. Shalini Agarwal S, Joshi MC, Kapoor AK. An analysis of prescription patterns in cases of uncomplicated hypertension in a tertiary care hospital. Natl J Integr Res Med. 2012;3(1):13-20. http://search.ebscohost.com/login.aspx?direct=true&db=a9h&AN=71533650&site=ehost-live. Accessed on August 21, 2017. [Google Scholar]
7. Kuchake VG, Maheshwari OD, Surana SJ, Patil PH, Dighore PN. Prescription pattern of antihypertensive drugs in uncomplicated hypertensive patients at teaching hospital. Indian J Pharm Pract. 2009;2(2):74-80.
http://www.ijopp.org/sites/default/files/IJOPP_v2_i2_2009_12.pdf. Accessed on August 21, 2017. [Google Scholar]
8. Ushadevi KH, Rubiya S, Vigneshwaran E, Reddy YP. Drug use evaluation of antihypertensive medications in out patients in a secondary care hospital. Asian J Pharm Clin Res. 2013;6(3):72-74. [Google Scholar]
9. Xavier D, Mathew N, Pradeep J, Pais P. Pattern of drug use in hypertension in a tertiary hospital : a cross-sectional study in the in-patient wards. Indian J Pharmacol. 2001;33:456-457. [Google Scholar]
10. Pai PG, Shenoy J, Sanji N. Prescribing patterns of antihypertensive drugs in a tertiary care hospital. Drug Invent Today. 2011;3(4):38-40. www.saspublisher.com. [Google Scholar]
11. Cidda M, Mateti U, Batchu M, Martha S. Study of prescribing patterns of antihypertensives in South Indian population. Int J Basic Clin Pharmacol. 2014;3(2):303-307. doi: 10.5455/2319-2003.ijbcp20140409. [CrossRef] [Google Scholar]
12. Wong MCS, Jiang JY, Griffiths SM. Switching of antihypertensive drugs among 93,286 Chinese patients: a cohort study. J Hum Hypertens. 2010;24(10):669-677. doi: 10.1038/jhh.2009.109. [PubMed] [CrossRef] [Google Scholar]
13. Li L, Liu D, Xie X, Dong P, Lin Y. Prescription patterns of antihypertensive medicines in China: a descriptive analysis in real-world conditions. In: Drummond M, Mullins CD, eds. Value in Health. Boston, MA: Elsevier; 2017:A1-A383.
https://www.ispor.org/ScientificPresentationsDatabase/Presentation/71227. Accessed September 28, 2017. [Google Scholar]
14. Beg M, Dutta S, Varma A, et al. Study on drug prescribing pattern in hypertensive patients in a tertiary care teaching hospital at Dehradun, Uttarakhand. Int J Med Sci Public Health. 2014;3(8):922-926. doi: 10.5455/ijmsph.2014.170420146. [CrossRef] [Google Scholar]
15. Sultana S, Hamid K, Islam KMS, et al. Assessment of prescription pattern of hypertensive patient’s prescription: a prescription survey study from various hospitals of Bangladesh. Eur J Sci Res. 2010;40(4):500-505.
https://www.researchgate.net/profile/Abu_Hasanat_Md_Zulfiker/publication/235999063_Assessment_of_Prescription_Pattern_of_Hypertensive_Patient%27s_Prescription_A_Prescription_Survey_Study_from_Various_Hospitals_of_Bangladesh/links/00b7d5156bcfc24bb9000000/Assessment-of-Prescription-Pattern-of-Hypertensive-Patients-Prescription-A-Prescription-Survey-Study-from-Various-Hospitals-of-Bangladesh.pdf. Accessed on August 21, 2017. [Google Scholar]
16. Alba-Leonel A, Carvajal A, Fierro I, et al. Prescription patterns of antihypertensives in a community health centre in Mexico City: a drug utilization study. Fundam Clin Pharmacol. 2016;30(3):276-281. doi: 10.1111/fcp.12179. [PubMed] [CrossRef] [Google Scholar]
17. Osibogun A, Okwor TJ. Anti-hypertensive prescription and cost patterns in an outpatient department of a teaching hospital in Lagos State Nigeria. Open J Prev Med. 2014;4(4):156-163. doi: 10.4236/ojpm.2014.44021. [CrossRef] [Google Scholar]
18. Akici A, Kalaça S, Uğurlu Ü, Toklu HZ, Oktay Ş. Antihypertensive drug utilization at health centres in a district of Istanbul. Pharm World Sci. 2007;29(3):116-121. doi: 10.1007/s11096-007-9103-5. [PubMed] [CrossRef] [Google Scholar]