Green synthesis of Annona muricata mediated selenium nanoparticles and its antifungal activity against Candida albicans
Main Article Content
Keywords
Annona, nanoparticles, Candida, muricata
Abstract
The emergence of antimicrobial resistance pathogens is threatening public health. Several conventional synthetic drugs are failed to treat resistant pathogens and cause adverse effects, alternative medicines are urgently needed. Recent research in nanomedicines is using our traditional plant materials and increasing their efficacy to treat antimicrobial pathogens. In this study, we have synthesized the Annona muricata-mediated selenium nanoparticles and assessed their antifungal activity against Candida albicans. The common fungi species of C. albicans are associated with various septic infections and oral diseases including oral cancer. In this study, the MIC test result revealed that Annona muricata-mediated selenium nanoparticles significantly inhibit C. albicans growth up to 75% at 100ul concentration. Therefore, AM-SeNPs could be used to treat multiple infections associated with C. albicans. Further research in AM-SeNPs may help bring this medicine to market in the future.
References
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19. López-Romero, B. A., Luna-Bárcenas, G., García-Magaña, M. L., Anaya-Esparza, L. M., Zepeda-Vallejo, L. G., López-García, U. M., Ortiz-Basurto, R. I., Aguilar-Hernández, G., Pérez-Larios, A., & Montalvo-González, E. (2022). Extraction of Acetogenins Using Thermosonication-Assisted Extraction from Annona muricata Seeds and Their Antifungal Activity. Molecules (Basel, Switzerland), 27(18), 6045. https://doi.org/10.3390/molecules27186045
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21. Pandiar D., Ramani P., Krishnan R.P., Dinesh Y, Histopathological analysis of soft tissue changes in gingival biopsied specimen from patients with underlying corona virus disease associated mucormycosis (CAM) doi:10.4317/medoral.25050
22. Abdel-Rahman, T., Hussein, S., Beshir, S., Hamed, A. R., Ali, E., & El-Tanany, S. S. (2019). Antimicrobial Activity of Terpenoids Extracted from Annona muricata Seeds and its Endophytic Aspergillus niger Strain SH3 Either Singly or in Combination. Open Access Macedonian Journal of Medical Sciences, 7(19), 3127-3131. https://doi.org/10.3889/oamjms.2019.793
23. Rosaiah, G., Mangamuri, U. K., Sikharam, A. S., Devaraj, K., Kalagatur, N. K., & Kadirvelu, K. (2022). Biosynthesis of Selenium Nanoparticles from Annona muricata Fruit Aqueous Extract and Investigation of their Antioxidant and Antimicrobial potentials. Current Trends in Biotechnology and Pharmacy, 16(1), 101-107.
24. Pandiyan I., Sri S.D., Indiran M.A., Rathinavelu P.K., Prabakar J., Rajeshkumar S.,Antioxidant, anti-inflammatory activity of Thymus vulgaris-mediated selenium nanoparticles: An in vitro study 2022 Journal of Conservative Dentistry
25. Paulraj J., Nagar P., Antimicrobial efficacy of triphala and propolis-modified glass ionomer cement: An in vitro study, 2020
2. Ezhilarasan Devaraj , Apoorva Velluru Ashok Vardhan Nandhigam: Syzygium cumini extract induced reactive oxygen species-mediated apoptosis in human oral squamous carcinoma cells , Journal of Oral pathology and medicine
3. Sato, T., Kishi, M., Suda, M. et al. Prevalence of Candida albicans and non-albicans on the tongue dorsa of elderly people living in a post-disaster area: a cross-sectional survey. BMC Oral Health 17, 51 (2017). https://doi.org/10.1186/s12903-017-0342-0
4. Patel, M. (2022). Oral Cavity and Candida albicans: Colonisation to the Development of Infection. Pathogens, 11(3). https://doi.org/10.3390/pathogens11030335
5. Cosola, M. D., Cazzolla, A. P., Charitos, I. A., Ballini, A., Inchingolo, F., & Santacroce, L. (2021). Candida albicans and Oral Carcinogenesis. A Brief Review. Journal of Fungi, 7(6). https://doi.org/10.3390/jof7060476
6. Vijayashree Priyadharsini J,Smiline Girija A.S.,Paramasivam A:In silico analysis of
virulence genes in an emerging dental pathogen A. baumannii and related species doi: 10.1016/j.archoralbio.2018.07.001
7. Ohshima, T., Ikawa, S., Kitano, K., & Maeda, N. (2018). A Proposal of Remedies for Oral Diseases Caused by Candida: A Mini Review. Frontiers in Microbiology, 9. https://doi.org/10.3389/fmicb.2018.01522
8. Charitos, I.A.; Topi, S.; Castellaneta, F.; D’Agostino, D. Current Issues and Perspectives in Patients with Possible Sepsis at Emergency Departments. Antibiotics 2019, 8, 56.
9. Pyrzynska, K., Sentkowska, A. Biosynthesis of selenium nanoparticles using plant extracts. J Nanostruct Chem 12, 467–480 (2022). https://doi.org/10.1007/s40097-021-00435-4
10. Priyadharsini, J.V., Biomedical Research Unit and Laboratory Animal Centre-Dental Research Cell [BRULAC-DRC], Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Tamil Nadu, Chennai, India doi:10.1002/JPER.18-0673
11. Doddanna, S. J., Patel, S., Sundarrao, M. A., & Veerabhadrappa, R. S. (2013). Antimicrobial activity of plant extracts on Candida albicans: an in vitro study. Indian journal of dental research : official publication of Indian Society for Dental Research, 24(4), 401–405. https://doi.org/10.4103/0970-9290.118358
12. Hsu, H., Sheth, C. C., & Veses, V. (2021). Herbal Extracts with Antifungal Activity against Candida albicans: A Systematic Review. Mini reviews in medicinal chemistry, 21(1), 90–117. https://doi.org/10.2174/1389557520666200628032116
13. Coria-Téllez, A. V., Montalvo-Gónzalez, E., Yahia, E. M., & Obledo-Vázquez, E. N. (2018). Annona muricata: A comprehensive review on its traditional medicinal uses, phytochemicals, pharmacological activities, mechanisms of action and toxicity. Arabian Journal of Chemistry, 11(5), 662-691. https://doi.org/10.1016/j.arabjc.2016.01.004
14. Souza, L. M. D. S., Dibo, M., Sarmiento, J. J. P., Seabra, A. B., Medeiros, L. P., Lourenço, I. M., Kobayashi, R. K. T., & Nakazato, G. (2022). Biosynthesis of selenium nanoparticles using combinations of plant extracts and theirantibacterial activity. Current Research in Green and Sustainable Chemistry, 5, 100303. https://doi.org/10.1016/j.crgsc.2022.100303
15. Campos, L. M., Lemos, A. S., Diniz, I. O., Carvalho, L. A., Silva, T. P., Dib, P. R., Hottz, E. D., Chedier, L. M., Melo, R. C., & Fabri, R. L. (2023). Antifungal Annona muricata L. (soursop) extract targets the cell envelope of multi-drug resistant Candida albicans. Journal of Ethnopharmacology, 301, 115856. https://doi.org/10.1016/j.jep.2022.115856
16. Proestos, C. (2020). The Benefits of Plant Extracts for Human Health. Foods, 9(11). https://doi.org/10.3390/foods9111653
17. Arjunkumar, R., Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, India, Nanomaterials for the management of periodontal diseases 2018 doi:10.1007/978-3-319-97634-1_11
18. Pai, B. M., Rajesh, G., Shenoy, R., & Rao, A. (2016). Anti-microbial Efficacy of Soursop Leaf Extract (Annona muricata) on Oral Pathogens: An In-vitro Study. Journal of Clinical and Diagnostic Research : JCDR, 10(11), ZC01. https://doi.org/10.7860/JCDR/2016/18329.8762
19. López-Romero, B. A., Luna-Bárcenas, G., García-Magaña, M. L., Anaya-Esparza, L. M., Zepeda-Vallejo, L. G., López-García, U. M., Ortiz-Basurto, R. I., Aguilar-Hernández, G., Pérez-Larios, A., & Montalvo-González, E. (2022). Extraction of Acetogenins Using Thermosonication-Assisted Extraction from Annona muricata Seeds and Their Antifungal Activity. Molecules (Basel, Switzerland), 27(18), 6045. https://doi.org/10.3390/molecules27186045
20. Olugbuyiro, J. A. O., Omotosho, O. E., Taiwo, O. S., Ononiwu, F. O., Banwo, A. S., Akintokun, O. A., ... & Ogunleye, O. M. (2018). Antimicrobial activities and phytochemical properties of Annona muricata leaf. Covenant Journal of Physical and Life Sciences, 5(2).
21. Pandiar D., Ramani P., Krishnan R.P., Dinesh Y, Histopathological analysis of soft tissue changes in gingival biopsied specimen from patients with underlying corona virus disease associated mucormycosis (CAM) doi:10.4317/medoral.25050
22. Abdel-Rahman, T., Hussein, S., Beshir, S., Hamed, A. R., Ali, E., & El-Tanany, S. S. (2019). Antimicrobial Activity of Terpenoids Extracted from Annona muricata Seeds and its Endophytic Aspergillus niger Strain SH3 Either Singly or in Combination. Open Access Macedonian Journal of Medical Sciences, 7(19), 3127-3131. https://doi.org/10.3889/oamjms.2019.793
23. Rosaiah, G., Mangamuri, U. K., Sikharam, A. S., Devaraj, K., Kalagatur, N. K., & Kadirvelu, K. (2022). Biosynthesis of Selenium Nanoparticles from Annona muricata Fruit Aqueous Extract and Investigation of their Antioxidant and Antimicrobial potentials. Current Trends in Biotechnology and Pharmacy, 16(1), 101-107.
24. Pandiyan I., Sri S.D., Indiran M.A., Rathinavelu P.K., Prabakar J., Rajeshkumar S.,Antioxidant, anti-inflammatory activity of Thymus vulgaris-mediated selenium nanoparticles: An in vitro study 2022 Journal of Conservative Dentistry
25. Paulraj J., Nagar P., Antimicrobial efficacy of triphala and propolis-modified glass ionomer cement: An in vitro study, 2020
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Published
Jun 26, 2023
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How to Cite
Arthi. S, Pratibha Ramani, & Rajeshkumar S. (2023). Green synthesis of Annona muricata mediated selenium nanoparticles and its antifungal activity against Candida albicans. Journal of Population Therapeutics and Clinical Pharmacology, 30(16), 282–287. https://doi.org/10.47750/jptcp.2023.30.16.038
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