Comparative Study of Serum Magnesium Levels in Diabetic Patients with And Without Microvascular Complications In A Tertiary Care Centre

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Nalabothu Sreelatha
Shanmuganandan Krishnan


Serum magnesium, Type 2 diabetes, Microvascular complications, HbA1c, Diabetes duration, Neuropathy


Background: It has been shown in several research that type 2 diabetes mellitus (DM) and its consequences with hypomagnesemia are related. Given that retinopathy, neuropathy, and nephropathy have been linked to hypomagnesemia in recent studies, it is advisable to routinely evaluate magnesium in this patient group and treat hypomagnesemia whenever possible. To compare type 2 diabetics' blood magnesium levels with microvascular problems was the goal of this study.
Methods: This research is a cross-sectional analytical study. About 114 diabetic patients from outpatient clinics, wards and intensive care unit were recruited from Department of General Medicine, Sri Balaji Medical College and Hospital, Crumpet, Chennai. The study population are further divided into two groups. Fifty-seven people with diabetes with microvascular complications (group I) have diabetes with no microvascular complications (group II). Clinical and physical examinations were done on all patients.
Results: Most diabetic patients (37%) aged 51 to 60 years, 54% male and 46% female. Approximately 26% of recruited patients had diabetes < 5 years, 44% were on insulin treatments, and 56% were oral hypoglycaemic agents. 57 diabetic people that have microvascular issues. Magnesium levels in the blood are noticeably greater in diabetics with microvascular difficulties than in those without issues. Between these two groups, no notable biochemical differences were discovered. Diabetic neuropathy is more likely to occur in patients who have had diabetes for a longer length of time.
Conclusions: We conclude that level of serum magnesium levels was found to be abnormally low with increasing diabetes duration along with microvascular complications. Type 2 diabetes patients who had hypomagnesemia were more likely to have long-term and microvascular problems.

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