Isolation and Characterisation of Bioactive Compounds from Methanolic Fraction of Aerial parts of Aspidopterys cordata
Main Article Content
Keywords
Bioactive, Phytochemistry, Pharmacy
Abstract
Background: The Present communication deals with Isolation of active bio compounds from Methanolic fraction of A.cordata
Method: Aerial components were ultrasonically extracted with methanol, fractionated using vacuum liquid chromatography, packed into silica gel columns, and their structures were determined using 1HNMR, 13CNMR, mass, and FTIR spectroscopies.
Results: The compounds isolated were characterised and were confirmed to be Ursolic acid a pentacyclic triterpenoid and Fisetin, dietary bioflavonol.
References
1. Basim, I., Jaber Kithar, A., & Majeed Alaa Gazi ALhashimi, R. (2021). Antioxidant and antibacterial activity of β-carotene pigment extracted from Paracoccus homiensis strain BKA7 isolated from air of Department of planning and follow up , Missan agriculture directorate , Ministry of agriculture-Iraq (Vol. 25). http://annalsofrscb.ro
2. Faridha Begum, I., Mohankumar, R., Jeevan, M., & Ramani, K. (2016). GC–MS Analysis of Bio-active Molecules Derived from Paracoccus pantotrophus FMR19 and the Antimicrobial Activity Against Bacterial Pathogens and MDROs. Indian Journal of Microbiology, 56(4), 426–432. https://doi.org/10.1007/s12088-016-0609-1
3. Feng, W., Li, M., Hao, Z., & Zhang, J. (2019). Analytical Methods of Isolation and Identification. In V. Rao, D. Mans, & L. Rao (Eds.), Phytochemicals in Human Health. IntechOpen. https://doi.org/10.5772/intechopen.88122
4. Kandasamy, S., Sahu, S. K., & Kandasamy, K. (2012). In Silico Studies on Fungal Metabolite against Skin Cancer Protein (4,5-Diarylisoxazole HSP90 Chaperone) . ISRN Dermatology, 2012, 1–5. https://doi.org/10.5402/2012/626214
5. K.N.Reddy, & C.Sudhakar Reddy. (2016). Flora of Telangana State, India. Bishen Shah Mahendra Pal SIngh.
6. Maurya, A., Kalani, K., Chandra Verma, S., Singh, R., Srivastava, A., & Journal, I. (2018). Organic & Medicinal Chem IJ Vacuum Liquid Chromatography: Simple, Efficient and Versatile Separation Technique for Natural Products Organic and Medicinal Chemistry. Organic & Medicinal Chem IJ, 7(2). https://doi.org/10.19080/OMCIJ.2018.07.555710
7. Monteiro Espíndola, K. M., Ferreira, R. G., Mosquera Narvaez, L. E., Rocha Silva Rosario, A. C., Machado Da Silva, A. H., Bispo Silva, A. G., Oliveira Vieira, A. P., & Chagas Monteiro, M. (2019). Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma. In Frontiers in Oncology (Vol. 9, Issue JUN). Frontiers Media S.A. https://doi.org/10.3389/fonc.2019.00541
8. Nisar, M., Shah, H., Khan, I., Fazal-Ur-Rehman, Khan, M. S., Marwat, S. K., Niazi, Z. R., & Ullah, A. (2013). Antimicrobial potential and phytochemical investigation of fixed oil of plant Chenopodium ambrosioides linn. Asian Journal of Chemistry, 25(2), 1069–1072. https://doi.org/10.14233/ajchem.2013.13439
9. P.Udaya Chandrika, & Dr.K.Sunitha. (2022). Evaluation of Phenolic, Flavonoid content and Antioxidant activity of Aspidopterys cordata: An Indigenous plant. NeuroQuantology, 20(8), 7469–7478.
10. Rasul, M. G. (2018). Extraction, Isolation and Characterization of Natural Products from Medicinal Plants. In International Journal of Basic Sciences and Applied Computing (IJBSAC) (Issue 6).
11. Rawal Jatin R, & Sonawani Priya R. (2016). Determination of Bioactive Components of Cynodon dactylon by GC-MS Analysis & it’s In Vitro Antimicrobial Activity. INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES, 71, 4880-4885].
12. Seo, S. Y., Kim, Y. J., Kim, J., Nam, M. H., & Park, K. Y. (2021). Phytosphingosine induces systemic acquired resistance through activation of sphingosine kinase. Plant Direct, 5(10). https://doi.org/10.1002/pld3.351
13. Sreedevi, A., Sangeetha, S., Achari, K. M. M., Sruthi, K. S., & Vadlamudi, Y. (2022). Phytochemical, in vitro and in silico screening of roots of Jasminum auriculatum for antioxidant activity. Eurasian Chemical Communications, 4(8), 768–777. https://doi.org/10.22034/ecc.2022.330488.1331
14. Teixeira, J., Gaspar, A., Garrido, E. M., Garrido, J., & Borges, F. (2013). Hydroxycinnamic acid antioxidants: An electrochemical overview. In BioMed Research International (Vol. 2013). https://doi.org/10.1155/2013/251754
15. T.Pullaiah. (2015). Flora of Telangana. The 29th state of India (Vol. 1). Regency Publications.
16. Udaya chandrika P, & Dr.Sunitha K. (2023). HR-LC-MS Phytochemical Profiling of A.cordata Methanolic Fraction and Antihypertension in Doca Salt-Induced Hypertensive Rats. European Chemical Bulletin, 12(1), 291–297.
17. Udaya Chandrika P, & Dr.Sunitha K. (2023). Phytochemical profiling by FTIR and GC-MS analysis of several fractions of Methanolic extract of aerial parts of A.Cordata. European Chemical Bulletin, 12(1), 308–317.
18. Udaya Chandrika Pulla, & Sunitha Katta. (2021). ACE Inhibitory Activity And Antihypertensive Effect Of Aspidopterys Cordata in DOCA-Salt-Induced Hypertension In Rats. Natural Volatiles and Essential Oils, 8(6), 4993–4999.
2. Faridha Begum, I., Mohankumar, R., Jeevan, M., & Ramani, K. (2016). GC–MS Analysis of Bio-active Molecules Derived from Paracoccus pantotrophus FMR19 and the Antimicrobial Activity Against Bacterial Pathogens and MDROs. Indian Journal of Microbiology, 56(4), 426–432. https://doi.org/10.1007/s12088-016-0609-1
3. Feng, W., Li, M., Hao, Z., & Zhang, J. (2019). Analytical Methods of Isolation and Identification. In V. Rao, D. Mans, & L. Rao (Eds.), Phytochemicals in Human Health. IntechOpen. https://doi.org/10.5772/intechopen.88122
4. Kandasamy, S., Sahu, S. K., & Kandasamy, K. (2012). In Silico Studies on Fungal Metabolite against Skin Cancer Protein (4,5-Diarylisoxazole HSP90 Chaperone) . ISRN Dermatology, 2012, 1–5. https://doi.org/10.5402/2012/626214
5. K.N.Reddy, & C.Sudhakar Reddy. (2016). Flora of Telangana State, India. Bishen Shah Mahendra Pal SIngh.
6. Maurya, A., Kalani, K., Chandra Verma, S., Singh, R., Srivastava, A., & Journal, I. (2018). Organic & Medicinal Chem IJ Vacuum Liquid Chromatography: Simple, Efficient and Versatile Separation Technique for Natural Products Organic and Medicinal Chemistry. Organic & Medicinal Chem IJ, 7(2). https://doi.org/10.19080/OMCIJ.2018.07.555710
7. Monteiro Espíndola, K. M., Ferreira, R. G., Mosquera Narvaez, L. E., Rocha Silva Rosario, A. C., Machado Da Silva, A. H., Bispo Silva, A. G., Oliveira Vieira, A. P., & Chagas Monteiro, M. (2019). Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma. In Frontiers in Oncology (Vol. 9, Issue JUN). Frontiers Media S.A. https://doi.org/10.3389/fonc.2019.00541
8. Nisar, M., Shah, H., Khan, I., Fazal-Ur-Rehman, Khan, M. S., Marwat, S. K., Niazi, Z. R., & Ullah, A. (2013). Antimicrobial potential and phytochemical investigation of fixed oil of plant Chenopodium ambrosioides linn. Asian Journal of Chemistry, 25(2), 1069–1072. https://doi.org/10.14233/ajchem.2013.13439
9. P.Udaya Chandrika, & Dr.K.Sunitha. (2022). Evaluation of Phenolic, Flavonoid content and Antioxidant activity of Aspidopterys cordata: An Indigenous plant. NeuroQuantology, 20(8), 7469–7478.
10. Rasul, M. G. (2018). Extraction, Isolation and Characterization of Natural Products from Medicinal Plants. In International Journal of Basic Sciences and Applied Computing (IJBSAC) (Issue 6).
11. Rawal Jatin R, & Sonawani Priya R. (2016). Determination of Bioactive Components of Cynodon dactylon by GC-MS Analysis & it’s In Vitro Antimicrobial Activity. INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES, 71, 4880-4885].
12. Seo, S. Y., Kim, Y. J., Kim, J., Nam, M. H., & Park, K. Y. (2021). Phytosphingosine induces systemic acquired resistance through activation of sphingosine kinase. Plant Direct, 5(10). https://doi.org/10.1002/pld3.351
13. Sreedevi, A., Sangeetha, S., Achari, K. M. M., Sruthi, K. S., & Vadlamudi, Y. (2022). Phytochemical, in vitro and in silico screening of roots of Jasminum auriculatum for antioxidant activity. Eurasian Chemical Communications, 4(8), 768–777. https://doi.org/10.22034/ecc.2022.330488.1331
14. Teixeira, J., Gaspar, A., Garrido, E. M., Garrido, J., & Borges, F. (2013). Hydroxycinnamic acid antioxidants: An electrochemical overview. In BioMed Research International (Vol. 2013). https://doi.org/10.1155/2013/251754
15. T.Pullaiah. (2015). Flora of Telangana. The 29th state of India (Vol. 1). Regency Publications.
16. Udaya chandrika P, & Dr.Sunitha K. (2023). HR-LC-MS Phytochemical Profiling of A.cordata Methanolic Fraction and Antihypertension in Doca Salt-Induced Hypertensive Rats. European Chemical Bulletin, 12(1), 291–297.
17. Udaya Chandrika P, & Dr.Sunitha K. (2023). Phytochemical profiling by FTIR and GC-MS analysis of several fractions of Methanolic extract of aerial parts of A.Cordata. European Chemical Bulletin, 12(1), 308–317.
18. Udaya Chandrika Pulla, & Sunitha Katta. (2021). ACE Inhibitory Activity And Antihypertensive Effect Of Aspidopterys Cordata in DOCA-Salt-Induced Hypertension In Rats. Natural Volatiles and Essential Oils, 8(6), 4993–4999.
Article Sidebar
Published
Jun 9, 2023
Article Details
How to Cite
Udaya Chandrika Pulla, & Sunitha Katta. (2023). Isolation and Characterisation of Bioactive Compounds from Methanolic Fraction of Aerial parts of Aspidopterys cordata. Journal of Population Therapeutics and Clinical Pharmacology, 30(14), 268–276. https://doi.org/10.47750/jptcp.2023.30.14.036
Section
Articles
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.