Measurement Serum Levels of Vitamin B12 in vitiligo Patients

Main Article Content

Ali Mohammed Abd AL-Ameer
Adil Mohammed Hashim
Asmaa Adnan Najm

Keywords

Melanin, Autoimmune diseases, Vitamin B12

Abstract

Vitiligo is a skin disease caused by a disorder in the work of the immune system that attacks melanocytes causing "to kill them and the loss of melanin pigment in the skin, several theories have been proposed to understand the causes of the occurrence of the disease, including the theory of autoimmune diseases, oxidative stress, neurological and genetic factors, including those related to exposure to some chemicals and the appearance of the disease may be associated with a decrease or increase in some vitamins, including vitamin B12, the aim of this research was to learn more about this vitamin because of its important effects on the system Blood and nervous system and its complex relationship to the skin and its association with the onset of the disease by measurement level's of concentration of vitamin B12 .
Methods: The current study included 120 participants as the control group (who appeared to be in good health) and 100 participants with vitiligo. These samples were obtained between 1 October to 15 December 2022, from the Dermatological Consultation Unit of the Imam Sadiq Teaching Hospital in the Babylon Governorate. ELISA test kits were used to measure the amount of vitamin B12 concentration in the serum of all patients and the control group.
Results: Serum for vitamins B12 levels significant decrease at the probability level (P≤0.05) of patient's with vitiligo, while evaluating the same-criteria rates for the control group.
Conclusions: In the current study, it was revealed Patients with vitiligo reported reduced serum for vitamins D levels compared to control group had.

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