Immunological Evaluation of Transforming Growth Factor beta In Patients With Bloody Diarrheal Infection In AL Najaf AL Ashraf Provency
Main Article Content
Keywords
bloody diarrhea, Entamoeba histolytica, diagnosis
Abstract
Amoebiasis causes up to 100.000 deaths annually all over the world, E. histolytica known as the main agent of intestinal amoebiasis causing amebic colitis. Amoebiasis is an infection caused by Entamoeba histolytica with or without symptoms. Replacements include amoebiosis, amoebic dysentery or bloody flux. This study comprised 150 blood sample from both gender (75 blood sample from patient bloody diarrhea with E.histolytica and 75 blood sample from patient with diarrhea but no diagnosis E.histolytica ) The result showed Serum level of TGF-beta in patient bloody diarrhea with E.histolytica and patient with diarrhea but no diagnosis E.histolytica.
References
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15. Wahid-Aldeen, E. I., Ahmad, N. A., & Sahlah Kh, A. S. (2009). Assessment of Lipid Profile and Cytokine (IL-13, TGF-β) with sICAM-1in Patients Infected with Intestinal Parasite (Entamoeba histolytica, Giardia lamblia and Blastocystis hominis).
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2. Alberta Health, and Wellness. (2011). Amoebiasis: Public health modifiable disease management guidelines.
3. Tanyuksel, M. and William P.H., 2005 .Laboratory diagnosis of amoebiasis . Clin. Microbio. Rev., 16:713-729.
4. Jaeffer, H.S. (2011). Prevalence of Gairdia lamblia and Entamoeba histolytic /Entamoeba dispare infections among Children in AL-Shulaa and AL-khadimya –Baghdad-Iraq. J. of university of Anbar for pure science. 5(2 ).
5. Nagaraja, S., & Ankri, S. (2019). Target identification and intervention strategies against amebiasis. Drug Resistance Updates, 44, 1-14
6. Wang, Y., & Zuo, X. (2019). Cytokines frequently implicated in myeloproliferative neoplasms. Cytokine: X, 1(1), 100005.
7. Bertolini, T. B., Biswas, M., Terhorst, C., Daniell, H., Herzog, R. W., & Piñeros, A. R. (2021). Role of orally induced regulatory T cells in immunotherapy and tolerance. Cellular immunology, 359, 104251.
8. Ngobeni, R., Ramalivhana, J. N., Traore, A. N., & Samie, A. (2022). Interleukin 10 (IL-10) Production and Seroprevalence of Entamoeba histolytica Infection among HIV-Infected Patients in South Africa. Pathogens, 12(1), 19.
9. Chou, A., & Austin, R. L. (2020). Entamoeba histolytica.
10. Saafa, R. S. S. A. D., & Al-Kaeebi, R. A. (2017). PCR conventional for detecting AP and PLA virulence Use factors of Entamoeba histolytica in patients stool samples in Al-Qadisiyah Province. Journal Of Wassit For Science & Medicine, 10(1).
11. Mohammed, H. S., Ali, S. A. K., Mohammed, L. O., & Mohammed, M. S. (2022). Prevalence of Amoebiasis and Estimation of Certain Cytokines (IL-17, IFN-γ and TNF-α) in Children with Amoebic Infection in Sulaimani Province/Iraq. Iraq Medical Journal, 6(1).
12. Al-Hilfi, A. A., Al-Malak, M. K., & Al-Tomah, M. A. (2021). A Prevalence study of Entamoeba spp. in Basrah Province using Different Detection Methods. Baghdad Science Journal, 18(4), 1163-1163.
13. Mohammed, H. S., Ali, S. A. K., Mohammed, L. O., & Mohammed, M. S. (2022). Prevalence of Amoebiasis and Estimation of Certain Cytokines (IL-17, IFN-γ and TNF-α) in Children with Amoebic Infection in Sulaimani Province/Iraq. Iraq Medical Journal, 6(1).
14. Sánchez-Alemán, E., Quintanar-Stephano, A., Escobedo, G., del Rosario Campos-Esparza, M., Campos-Rodríguez, R., & Ventura-Juárez, J. (2015). Vagotomy induces deregulation of the inflammatory response during the development of amoebic liver abscess in hamsters. Neuroimmunomodulation, 22(3), 166-180.
15. Wahid-Aldeen, E. I., Ahmad, N. A., & Sahlah Kh, A. S. (2009). Assessment of Lipid Profile and Cytokine (IL-13, TGF-β) with sICAM-1in Patients Infected with Intestinal Parasite (Entamoeba histolytica, Giardia lamblia and Blastocystis hominis).
16. Fukata, M. (2012). Innate Immunity: A Potent Target for Management of Inflammatory Bowel Disease. In Colitis. IntechOpen.
17. Verma, R. N., Malik, M. Z., Subbarao, N., Singh, G. P., & Sinha, D. N. (2022). Entamoeba histolytica HM-1: IMSS gene expression
profiling identifies key hub genes, potential biomarkers, and pathways in Amoebiasis infection: a systematic network meta-analysis. Bioscience Reports, 42(10), BSR20220191.
18. Melby, P. C., Stephens, R., & Dann, S. M. (2019). Host defenses to protozoa. In Clinical Immunology (pp. 425-435). Elsevier.
19. Samanta, S. (2023). Mechanisms of gastrointestinal pathogenesis and landscape of intestinal immunity. In Viral, Parasitic, Bacterial, and Fungal Infections (pp. 863-913). Academic Press.
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Published
Jun 1, 2023
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How to Cite
Raad Ajam Sayl, & Nada Ahmed Abbas. (2023). Immunological Evaluation of Transforming Growth Factor beta In Patients With Bloody Diarrheal Infection In AL Najaf AL Ashraf Provency. Journal of Population Therapeutics and Clinical Pharmacology, 30(12), 73–78. https://doi.org/10.47750/jptcp.2023.30.12.010
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