Study the Effect of chemical treatments on the physiological and biochemical parameters of patients with cancerous diseases in Thi-Qar Governorate

Main Article Content

Ghada Majeed Lafah
Mohannad Abdulrazzaq Gati

Keywords

Cancerous disease, chemical treatments

Abstract

This research was designed to study the impact of chemotherapy on cancer patients' physiological and biochemical alterations in Thi-Qar Governorate. The study included 138 participants and 46 women with breast cancer divided into 23 samples taken (1-5 doses) and 23 took more than 5 doses The treatment was Paclitaxel and Carboplatin., and 46 males with liver cancer divided into 23 samples taken (1-5 doses) and 23 took more than 5 doses The treatment was Doxorubicin. 46 healthy individuals, 23 males and 23 females. The study was conducted in Al-Haboubi Hospital, Department of Oncology, in Thi-Qar Governorate, for the period between December 2022 - February 2023. With regard to blood parameters, the results showed a clear decrease in hemoglobin, red blood cells, white blood cells, and platelets in males and females who were treated with chemotherapy. As for liver enzymes, we notice an increase in ALT and AST in males with liver cancer more than in females with breast cancer. As for the ALP enzyme, we notice an increase in both sexes, and there is no significant difference between them. As for lipid , it is noted that there are clear changes, an increase in cholesterol and TG, a decrease in HDL in both sexes. For the hormones that are LH and E2, we notice a clear decrease in the value of the hormones compared to the normal level. For males, we notice a clear decrease in FSH and testosterone compared to the normal level.

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