Impact of ferritin level on testicular size in hemodialysis patients

Mohamed A. Abdelrahman; Tamer Abdel Tawab Hasan; Abdelfattah Farag; Mostafa Elshafie; Ibrahim M. Abd Elazim; Osama Mosbah

doi:10.47750/jptcp.2023.30.07.038

Mohamed A. Abdelrahman

Department of Nephrology, Theodor Bilharz Research Institute, Giza, Egypt

Tamer Abdel Tawab Hasan

Department of Nephrology, Theodor Bilharz Research Institute, Giza, Egypt

Abdelfattah Farag

Department of Andrology and Sexually Transmitted Disease, Cairo University, Egypt

Mostafa Elshafie

Department of Radiology, Theodor Bilharz Research Institute, Giza, Egypt

Ibrahim M. Abd Elazim

Department of critical care medicine, Theodor Bilharz Research Institute, Giza, Egypt

Osama Mosbah

Department of Nephrology, Theodor Bilharz Research Institute, Giza, Egypt

Keywords

ferritin- testes-testicular size-testicular volume- hemodialysis-ESRD

Abstract

Background: Iron deficiency anemia is common among ESRD patients on regular hemodialysis. Upon that erythropoiesis-stimulating agents and iron supplementation are essential. Being a good marker that reflect body iron stores, ferritin is used to evaluate the iron overload status to monitor iron therapy in chronic kidney disease patients.
Aim of work: To determine the effect of ferritin level on the testicular size in ESRD patients on regular hemodialysis.
Patients and Methods: We recruited 150 male ESRD on regular HD three times per week divided into 3 groups according to hemodialysis duration (group A: those on HD for at least 3 years, group B: those on HD for at least 6 years and group C: those on HD for at least 9 years) and 50 healthy controls. Scrotal ultrasound to assess testicular volume and ferritin level as a part of iron profile were done.
Results: Our study demonstrates that the testicular size was inversely correlated to ferritin level and duration of hemodialysis in the 3 HD groups when compared to controls (p-value: <0.0001).
Conclusion: ferritin level can be used as a diagnostic test to predict the testicular volume with sensitivity 91% and specificity 97% (p-value: <0.0001).

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Published

Apr 15, 2023

DOI https://doi.org/10.47750/jptcp.2023.30.07.038

How to Cite

Mohamed A. Abdelrahman, Tamer Abdel Tawab Hasan, Abdelfattah Farag, Mostafa Elshafie, Ibrahim M. Abd Elazim, & Osama Mosbah. (2023). Impact of ferritin level on testicular size in hemodialysis patients. Journal of Population Therapeutics and Clinical Pharmacology, 30(7), 314–321. https://doi.org/10.47750/jptcp.2023.30.07.038