ANALYSIS OF LAKSHADIGANA TAILA: A TRIAL AYURVEDIC FORMULATION TO HEAL INFECTED WOUNDS (DUSHTA VRANA)
Main Article Content
Keywords
Lakshadigana Taila, Analysis, Infected Wound, Dushta Vrana, Antimicrobial activity.
Abstract
Background
Due to awareness and general acceptability for the use of herbal drug in today’s medical practice. Standardization of herbal formulation is essential in order to assess the quality, purity, Safety and efficacy of drug which is based on amount of their active constituents. Newer guidelines for standardization, manufacture, quality control and scientifically rigorous research are essential for traditional treatments for its global acceptance. Herbal drugs induce healing by a number of modes of action. Because of their traditional applicability, affordability and safety plants gained a reputed position in the world of Infected wound (Dushta Vrana) management but scientific evidence for their wound healing potentials is less.
Aim
To Analysis of trial drug Lakshadigana Taila and its ingredients.
Materials and methods
Four most available plants in local area of Banaras Hindu University plants were selected to make a Ayurvedic formulation in the form of Taila for Shodhana and Ropana of Dushta Vrana (Infected Wound). These plants were Laksha, Nimba, Haridra and Amaltas from Lakshadigana of Sushruta Samhita and after discussion it named as Lakshadigana Taila. This was used to treat patients of Dushta Vrana (Infected chronic wounds).
Investigation performed: Macro-Microscopy, pH, Methylation & GC-MS identification of Medicated Oil (Base – Til oil) Sesamum indicum
Sample details: Medicated oil (Base – Til oil) Sesamum indicum, Laksha, Nimba, Haridra and Aragvadha.
Results
By Observing analysis of Lakshadigana Taila and its ingredients it is clear that this trial drug can be used as in Dushta Vrana (Infected chronic wound) due to its antimicrobial activity (Vranashodhana Activity). Many supportive finding like analysis and antimicrobial activity of Lakshadigana Taila and its four drugs (Laksha, Nimba, Haridra and Amaltas with Til Taila (Sesame oil) indicate that it having Vranaropaka activity too.
References
2. Gupta LC, Gupta K and Gupta A: New Concise Medical Dictionary. AITBS, Delhi, Fourth Edition, 2008.
3. Samuel R.Nussbaum,MD1, MarissaJ.Carter,PhD,MA2, CarolineE.Fife,MD3,4,5, Joan DaVanzo,PhD,MSW6, RandallHaught6, MarciaNusgart,RPh7,*, DonnaCartwright,MPA8, An Economic Evaluation of the Impact, Cost, and Medicare Policy Implications of Chronic Nonhealing Wounds, VALUE IN HEALTH 21(2018)27
4. Prabuseenivasan S, Jayakumar M, Ignacimuthu S. In vitro antibacterial activity of some plant essential oils. BMC Complementary and Alternative Medicine (2006), 6:39
5. Kumar S, Lincy Joseph L, George M, Bharti V. Antimicrobial activity of methanolic extracts of Rumex nepalensis leaves. Int J Pharm Pharm Sci 2011; 3(4): 240-242.
6. Bhalodia et al: Antimicrobial activity of cassia fistula linn. Ayu journal(2012);33(1):124

