COMPARISON OF URIC ACID LEVELS AMONG NORMOTENSIVE AND HYPERTENSIVE SUBJECTS
Main Article Content
Keywords
Hypertension, Uric acid, Hyperuricemia, Normotension, Polyuria
Abstract
Background
Hyperuricemia has been implicated in hypertension and cardiovascular disease, but comparative data remain debated.
Objective: To compare serum uric acid levels between normotensive and hypertensive subjects and evaluates associated symptom distributions and gender differences.
Methods: A cross‑sectional study of 80 subjects was conducted. This study was conducted at University of Lahore, Lahore. Subjects were classified as hypertensive if systolic blood pressure measured ≥140 mmHg or diastolic blood pressure measured ≥90 mmHg. Serum uric acid levels between two groups were compared using student t-test. Symptom prevalence and gender differences were analyzed using chi‑square and subgroup comparisons.
Results: Of 80 subjects, 41 were hypertensive and 39 normotensive subjects. Mean uric acid was significantly higher in hypertensive subjects (6.3 ± 0.23 mg/dL) compared to normotensive subjects (4.9 ± 0.18 mg/dL, p<0.05). Joint pain (p=0.03), polyuria (p=0.04), and general weakness (p=0.05) were more prevalent in hypertensive individuals. Hypertensive males showed significantly higher uric acid levels (6.6 ± 0.28 mg/dL) compared to hypertensive females (6.0 ± 0.30 mg/dL, p=0.04).
Conclusion: Raised uric acid levels are significantly linked with high blood pressure and symptom burden.
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Sheraz Hassan
Leabaib Health Centre, primary health care corporation Doha Qatar,
Rula Al-Baghdadi
Consultant family medicine-department of family and community medicine (PHCC)
Sajjad Karamat
Senior Demonstrator, Department of Pharmacology, SIMS, Lahore
Nabeel Umer Hussain
Consultant Family Medicine PHCC (Primary health care Corporation), Qatar
