METABOLIC SYNDROME AND EARLY RENAL DYSFUNCTION: A CROSS-SECTIONAL ANALYSIS IN AN URBAN INDIAN POPULATION
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Keywords
Metabolic Syndrome, Early renal dysfunction, Chronic Kidney disease, Obesity
Abstract
Metabolic syndrome (MetS) is an escalating public health problem and is increasingly recognised as a contributor to early renal dysfunction. This study evaluated the association between MetS severity and renal function markers in an urban Indian population. Among 1000 screened individuals, 350 met the NCEP-ATP III criteria for MetS. Participants were stratified into three groups based on the number of MetS components present. Anthropometric, biochemical, and renal parameters were analysed. Progressive worsening of fasting glucose, lipid abnormalities, serum urea, uric acid, estimated glomerular filtration rate (eGFR), and urinary markers was observed with increasing MetS components. Central obesity showed significant correlations with multiple renal indices. These findings emphasise the importance of routine renal monitoring in individuals with MetS to enable early detection of kidney involvement.
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Simmi Dubey
Ph.D Scholar, Dept.of Physiology, Malwanchal University, Indore, MP
Dr.Ashutosh Jain
Associate Professor, Dept.of Physiology, IMCH&RC, Malwanchal University, Indore, MP
