PHYTOCHEMICAL INVESTIGATION, ANTI-OXIDANT ASSAY OF FICUS GLOMERATA AND AEGLE MARMELOS EXTRACTS
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Keywords
Medicinal plants, Ficus glomerata, Aegle marmelos, Anti-oxidant assay
Abstract
Medicinal plants are a rich source of bioactive compounds with significant therapeutic potential, particularly as natural antioxidants. This study evaluated the phytochemical composition, antioxidant content, and antioxidant activity of methanolic and chloroform extracts of Ficus glomerata and Aegle marmelos leaves. The plants were collected, authenticated, shade-dried, powdered, and subjected to Soxhlet extraction using methanol and chloroform. Preliminary phytochemical screening revealed the presence of alkaloids, flavonoids, saponins, reducing sugars, and phenolic compounds in both plant extracts, with methanol extracts generally exhibiting a richer profile. Antioxidant activity was assessed using DPPH radical scavenging, total flavonoid content, reducing power, and total polyphenolic content assays. Methanolic extracts showed higher DPPH scavenging activity with IC50 values of 98.78 µg/mL (F. glomerata) and 101.23 µg/mL (A. marmelos), whereas chloroform extracts demonstrated slightly lower activity. Total flavonoid content ranged from 0.268–0.342 QE mg/100 mg, and reducing power and polyphenolic content were higher in methanolic extracts. These findings highlight the significant antioxidant potential of both plants, supporting their traditional use and potential development as natural antioxidant sources.
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Pankaj Kumar Shankhdhar
Ph.D. Scholar1, Professor and Principal3, BIU College of Pharmacy, Bareilly International University, Bareilly (U.P.)
Dr. Pankaj Mishra
Professor and Principal2, Rohilkhand College of Pharmacy, Bareilly International University, Bareilly (U.P.)
Dr. Pushpendra Kannojia
Professor and Principal3, BIU College of Pharmacy, Bareilly International University, Bareilly (U.P.)
Rohit Kumar Bijauliya
Ph.D. Scholar1, Professor and Principal3, BIU College of Pharmacy, Bareilly International University, Bareilly (U.P.)
