“COMPARISON OF IV MGSO4 & PLACEBO IN EMERGENCE AGITATION IN PEDIATRIC POPULATION UNDERGOING GENERAL ANESTHESIA”
Main Article Content
Keywords
Emergence agitation, magnesium sulfate, pediatric anesthesia, general anesthesia, postoperative recovery.
Abstract
Introduction: Emergence agitation (EA) is among the frequent post-anesthetic conditions in pediatrics and it is defined by confusion, restlessness, and aggression. A possible solution to EA has been proposed to be magnesium sulfate (MgSO4) because magnesium sulfate is neuroprotective and sedative.
Objective: To assess the intravenous magnesium sulfate efficacy in comparison to placebo in the eventual reduction of emergence agitation in pediatric patients under general anesthesia.
Materials and Methods: A randomized controlled trial was carried out at Sheikh Zayed Medical College/Hospital, Rahim Yar Khan, from 1 April 2025 to 30 June 2025. Pediatric patients aged 3-12 years were randomly divided to receive either magnesium sulfate (20 mg/kg) or a placebo during the operation. The recording of the rates as well as the times of the emergence of agitation was done in both groups.
Results: The MgSO4 group demonstrated a significantly lower rate of severe agitation (10%) as well as a shorter duration of agitation (3.5 minutes) in comparison to the placebo group (30%, 6.2 minutes).
Conclusion: Magnesium sulfate administered intravenously is effective in lowering the rate as well as the duration of emergence agitation in children after general anesthesia.
References
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Dr Alina Zafar
Senior Registrar Anesthesia & ICU, Shiekh Zayed Mdical College / Hospital, Rahim Yar Khan
Email: docaleena786@gmail.com
Dr Moosa Kaleem
Medical Officer Anesthesia & ICU, Shiekh Zayed Medical College/ Hospital, Rahim Yar Khan
Email: moosakaleem456@gmail.com
Dr Haqdad Durrani
Professor Anesthsia & ICU, Director Medical Education, Ghazi Medical College/ Hospital, Dera Ghazi Khan, Email: profhaqdad@gmail.com
