TO COMPARE THE EFFICACY OF INSTASEAL (ISO AMYL 2-CYANOACRYLATE, BIO-ADHESIVE) WITH 3-0, ETHICON MERSILK, IN SURGICAL WOUND CLOSURE AFTER ALVEOLOPLASTY.
Main Article Content
Keywords
Bilateral Alveoloplasty, Iso amyl 2-cyanoacrylate, Bioadhesive , 3-0 mersilk suture, efficacy of Instaseal
Abstract
To evaluate the efficacy of instaseal (iso amyl 2-cyanoacrylate) in closure of surgical Wound after alveoloplasty in comparison with ethicon mersilk, 3-0 sutures.
Objectives-This study was done to compare the clinical efficacy of surgical wounds in cases of alveoloplasty when wound closure was done by isoamyl 2-cyanoacrylate adhesive and 3-0 ethicon mersilk.
Methodology - The present prospective randomized study was conducted in PDM Dental College and Research Institute, Bahadurgarh in the department of oral and maxillofacial surgery after attaining the ethical committee clearance.Total number of 30 patients with age range 35-75yrs in which 17 male and 13 female were studied requiring bilateral alveoloplasty in anterior and posterior region of the lower and /or upper edentulous arch and closed randomly on one side with 3-0 black mersilk suture and on the other side with iso amyl 2-cyanoacrylate glue. The surgical sites were evaluated on the first hour of the same day and third, seventh, fourteenth postoperative days for any pain, bleeding, inflammation, infection, dehiscence and allergy.
Result-Pain and inflammation appeared to be reduced on the glued side, suggesting faster healing. Thus, it is evident from the study that iso amyl 2-cyanoacrylate glue aids in early initial healing, Is easy to apply, safe, less time consuming, less tissue reaction, no need for its removal as it is Biodegradable and no need of pressure pack. Some other advantages are simplicity, higher Speed, and excellent (grade 1) hemostasis. Based on the present study there was statistically no significant difference in p-value>0.05 between the two groups, group I and group II in relation to all the parameter evaluated and analyzed like pain, bleeding, inflammation, infection, dehiscence and allergy. Except the time efficiency which showed a significant p-value < .000 suggesting less time consumed in group II (glue site) as compared to group I (suture site). Hence the two materials are comparable in all aspects.
Conclusion-The result suggested that isoamyl-2-cyanoacrylate has better initial healing compared to suture and was easy and safe to use.
References
2. G. E. Ghali, Peter E. Larsen, Peter D. Waite Wound healing Principles of Oral and Maxillofacial Surgery; vol 1.
3. Reece TB, Maxey TS, Kron IL. A Prospective on tissue adhesives. Am J Surg. 2001; 182 (2 Suppl):40S-4S.
4. Vastani A, Maria A. Healing of Intraoral Wounds Closed Using Silk Sutures and Iso amyl 2-Cyanoacrylate Glue: A Comparative Clinical and Histologic Study. J Oral Maxillofac Surg. 2013;71:241-8.
5. Gassener R. Wound closure materials. Oral Maxillofacial Surg Clin N Am. 2002;14:95-104.
6. Ghoreishian M, Gheisari R, Fayazi M. Tissue adhesive and suturing for closure of the surgical wound after removal of impacted mandibular third molars: A comparative study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108:e14-6.
7. Bhaskar S.N et al Oral tissue response to chemical adhesives (Cyanoacrylates). Oral surg, Oral Med, Oral Path. 1966;22:394.
8. Bhaskar S.N.et al. Oral Spray of isobutyl cyanoacrylate & its systemic effect. Oral Surg Oral Med Oral Pathol. 1970 Feb;29(2):313.
9. Greer RO jr. Studies concerning the histotoxicity of lsobutyl-2-cyanoacrylate tissue adhesive when applied as an oral hemostat. Oral Surg Oral Med Oral Pathol. 1975;40:659-69.
10. Gali KA, Schofield ID, Wright GZ. Effect of N-Butyl2- Cyanoacrylate (Histocryl) on healing of skin wounds. J. Can Dent Assoc. 1984;50:565.
11. Rajaseharan A. The effectiveness of lsoamyl 2 cyanoaciylate. Clinics Of Pharmaco.Plastic ans Reconstr Surg. 1999;91:371-77.
12. Soni A, Narula R, Kumar A, Parmar M. Comparing Cyanoacrylate Tissue Adhesive and Conventional Subcuticular Skin Sutures for Maxillofacial Incisions—A Prospective Randomized Trial Considering Closure Time, Wound Morbidity, and Cosmetic Outcome. J Oral Maxillofac Surg. 2013;71:2152.e1-2152.e8.
13. Quin J, Wells.J, Scutliffe.T et al. Comparative study of infected wounds closed with cyanoacrylate and sutures. JAMA. 1997;277:1527-30.
14. Matin SF. Prospective randomized trial of skin adhesive versus sutures for closure of 217 laparoscopic port-site incisions. J Am Coll Surg 2003;196:845.
15. Cheng W, Saing H. A prospective randomized study of wound approximation with tissue glue in circumcision in children. J Paediatr Child Health 1997;33:515.
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Dr Jitender
Assistant Professor, Oral & Maxillofacial Surgery Department, PDM Dental College & Research
Institute, Bahadurgarh, Haryana.
(8529494514, jitu692@gmail.com)
Dr Anchal Bhardwaj
BDS, MDS, Periodontology & Oral Implantology, Jaipur, Rajasthan
(8502806448, dixit8anchal@gmail.com)
Dr Varun Arora
BDS, MDS, Periodontology & Oral Implantology, Resident Kalpana Chawla Govt. Medical College, Karnal, Haryana
(9416000605, varunarora19852002@gmail.com)
