COMPARATIVE EVALUATION OF 4% ARTICAINE AND 2% LIDOCAINE (1:100,000 EPINEPHRINE) FOR INFERIOR ALVEOLAR NERVE BLOCK IN MANDIBULAR THIRD MOLAR SURGERY
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Keywords
Efficacy, Articaine, Lidocaine, Impacted, Mandibular third molar, Randomized study
Abstract
This study compares the anesthetic efficacy of 4% Articaine versus 2% Lidocaine, both with epinephrine 1:100,000, administered via the inferior alveolar nerve block technique during the surgical extraction of bilateral impacted lower third molars.
Study design: A randomized double-blind clinical study was conducted on 40 patients that required bilateral surgical extraction of impacted lower third molars. Each patient was administered 4% articaine on one side and 2% lidocaine on other side with the same concentration of vasoconstrictor (epinephrine 1:100,000). The following study variables for each anesthetic solution were assessed: latency (time to onset), duration of anesthetic effect, the amount of anesthetic solution used, haemodyanamic parameters.
Result: Statistically significant differences were seen in the onset and duration of anesthesia. Articaine demonstrated a faster onset and a significantly longer duration of action when compared with lidocaine. No significant difference were observed in both the anesthetic agent group in the context of other hemodynamic parameters (Blood pressure, oxygen saturation, respiratory rate,)
Conclusion: When comparing the latency and duration of the anesthetic action, 4% articaine performs better than 2% lidocaine clinically. Other hemodynamic characteristics, however, did not show any statistically significant variations.
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Dr. Pallavi Rai
MDS, Oral and Maxillofacial Surgery, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttar Pradesh, India
Prof. Dr. Hemant Mehra
MDS, Oral and Maxillofacial Surgery, Saraswati Dental College and Hospital, Lucknow, Uttar Pradesh, India
Dr. Abhijeet Humne
MDS, Oral and Maxillofacial Surgery, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttar Pradesh, India
Prof. Dr. Hemant Gupta
MDS, Oral and Maxillofacial Surgery, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttar Pradesh, India
