Assessment of the Hormonal Background of Saliva and Blood in Patients with an Inflammatory-Destructive Process in the Periodontium Against the Background of Hepatitis C
Main Article Content
Keywords
periodontitis, sex hormones of blood and saliva
Abstract
The aim of this study was to elucidate the role of the hormonal background of the oral fluid and blood in patients with pathological conditions in periodontal tissues against the background of hepatitis C. 62 patients aged 26 to 40 years with a diagnosis of hepatitis C were examined. Using the enzyme immunoassay method, the content of blood sex hormones and mixed saliva. There was a decrease in the concentration of testosterone by 35%, estradiol - by 32% and progesterone by 2.5 times in the blood relative to the indicators of the control groups. In the mixed saliva of the examined, a decrease in the content of testosterone by 44%, estradiol - by 59% and progesterone - by 52% was revealed.
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3. Vavilova T.P. Biochemistry of tissues and fluids of the oral cavity: a textbook. M.: GEOTARMedia, 2019. -208 p.
4. Khaidarov A.M. Kamilov Kh.P. The need for periodontal treatment according to the CPITN index in patients with hypothyroidism. Honey.
Journal of Uzbekistan, 2010 No. 5. pp. 49-51.
5. Vavilova T.P. Ostrovskaya I.G. Medvedev A.E. Opportunities and prospects for the study of hormones in saliva / Biomedical Chemistry. -
2014. - T.60, issue 3. -FROM. 295-307.
6. Khaidarov A.M. Kamilov Kh.P. X-ray picture of the alveolar part of the jaw in patients with periodontitis with hypothyroidism. Journal of
Dentistry, No. 3-4, 2010 pp. 275-277.
7. Vavilova T.P., Shtrunova L.N., Shishkin S.V. et al. The use of indicators of mixed saliva in assessing the state of periodontal tissues //
Russian Dental Journal. -2010. -№1. -p.10-13.
8. Khaidarov A.M. Clinical efficacy of treatment of periodontitis in patients with hypothyroidism. Medical Journal of Uzbekistan, 2011 No. 1. pp.
14-17.
9. Dombrovskaya Yu.A. Influence of age-related androgen deficiency on the formation of pathology of periodontal tissues and oral mucosa / Yu.A. Dombrovskaya, A.V. Pechersky, V.N. Ellinidi, I.A. Frost // Institute of Dentistry. - 2007. - V.1. - No. 34. - р. 78 -79.
10. Dombrovskaya Yu.A. Influence of age-related androgen deficiency on the formation of pathology of periodontal tissues and oral mucosa
/ Yu.A. Dombrovskaya, A.V. Pechersky, V.N. Ellinidi, I.A. Frost // Institute of Dentistry. - 2007. - V.1. - No. 34. - р. 78 -79.
11. Katkhanova L.S., Akulova E.V., Lysov A.V., Mogila A.P. Influence of hormonal regulation on the state of periodontal tissues // Bulletin of the
Medical Internet Conference. - 2014. -V.4, No. 12. - р. 77-79.
12. Khaidarov A.M., Kamilov Kh.P. Muydinova M.Sh. Clinical assessment of the periodontal condition in patients with hypothyroidism,
Medical Journal of Uzbekistan, 2011 No. 5. pp. 18-20.
13. Yanushevich O.O., Syrbu O.N. The role of sex hormones in the pathogenesis of chronic generalized periodontitis (literature review) //
Russian Dentistry. -2014. -No. 7. -р. 3-7.
14. Khaidarov A.M., Kamilov Kh.P. Dynamics of mineralization of the alveolar process of the jaw during osteotropic therapy of periodontitis in
patients with hypothyroidism. Scientific and practical journal Doctor-Postgraduate, 2011 № 6.3(49), pp. 490-495.
15. Khaidarov A.M., Rizaev Zh.A. Medical Ecology: Environmental Pollutants Proceedings of the XV International Conference. Ecology and
development of society St. Petersburg 2014. pp. 22-26.
16. Rustamova S. M. et al. Evaluation of the concentration of short-chain fatty acids in the oral fluid in patients with chronic periodontitis //Asian journal of pharmaceutical and biological research. – 2022. – Т. 11. – №. 3.
17. Khaidarov A.M., Rizaev Zh.A. Evaluation of the results of examination of the oral cavity of children living in the area where industrial enterprises are located. Bulletin of the Tashkent Medical Academy, 2014 No. 3, pp. 89-91.
18. Khaidarov A.M., Rizaev Zh.A. The prevalence and intensity of dental caries in children living in the territory of ecological risk. Journal of Dentistry, No. 3-4, 2014 pp. 10-16.
19. Khaidarov A.M., Rizaev Zh.A. Rustamova D.A. Rizaev E.A. The study of the intensity and prevalence of periodontal diseases based on patient surveys. Journal of Dentistry, No. 1-2, 2015 pp. 150-154.
20. Abduyusupova K.M., Khaidarov A.M., Khozhmitov A.A. Significance of dysregulation of endothelial functions in the development of exfoliative cheilitis, Journal of Biomedicine and Practice No. 6 2022 pp. 268-277.
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Published
Mar 13, 2023
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How to Cite
Abduyusupova Kamola Mirvalievna, Khaidarov Artur Mikhailovich, & Khadjimetov Abdugafur Ahadovich. (2023). Assessment of the Hormonal Background of Saliva and Blood in Patients with an Inflammatory-Destructive Process in the Periodontium Against the Background of Hepatitis C. Journal of Population Therapeutics and Clinical Pharmacology, 30(3), 480–484. https://doi.org/10.47750/jptcp.2023.30.03.050
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