THE ROLE OF FUNGI IN THE PATHOGENESIS OF PERIODONTITIS: A SYSTEMATIC REVIEW
Main Article Content
Keywords
Fungi, Candida, Periodontitis, Candida albicans, Systematic review, Meta Analysis
Abstract
The association between periodontitis and specific bacterial pathogens are well established. However, Fungal organisms, particularly Candida species, have been frequently detected in periodontal pockets, with Candida albicans being the most commonly isolated species.
Aim: The aim of the present study is to evaluate the role of fungi in pathogenesis of periodontitis through a systematic review.
Material and method: Literature search was performed in various electronic databases for articles published upto December 31 2024. Two reviews independently reviewed the articles. Five studies were selected based on the inclusion criteria. The Joanna Briggs Institute Critical Appraisal Checklist for Quasi-Experimental Studies was used to evaluate the risk of bias in the included studies.
Results: Five studies (cross sectional Study -4, and case control -1) were selected based on the inclusion and exclusion criteria. The findings of this Systematic review suggests that there is a strong association between the presence of Candida species and periodontal diseases.
Conclusion:
Fungal organisms, particularly Candida species, are found to be associated with periodontal pockets. Therefore, periodontitis that is resistant to conventional treatment may require additional broad spectrum antibiotics for coverage of fungal organisms also.
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Balasubramaniam Vajravel
Postgraduate Student, Department of Periodontology and Implantology, Sree Balaji Dental College and Hospital, Chennai, India, Bharath Institute of Higher Education and Research, Chennai – 600100, Tamil Nadu, India.
Kaviya Priya
Postgraduate Student, Department of Periodontology, SRM Dental College, Bharathi Salai, Ramapuram, Chennai -600089, Tamil Nadu, India.
Swarna Kesavan
B.D.S., Sri Ramakrishna Dental College and Hospital, SNR College Road, Coimbatore-641006
Dr Rudhra Kannan
Assistant Professor, Department of Periodontology, Sree Balaji Dental College and Hospital, Chennai, India, Bharath Institute of Higher Education and Research, Chennai – 600100, Tamil Nadu, India.
Anitha Balaji
BDS, MDS, PhD, Professor and Head, Department of Periodontology, Sree Balaji Dental College and Hospital, Chennai, India, Bharath Institute of Higher Education and Research, Chennai – 600100, Tamil Nadu, India.