COMMON GASTRIC MANIFESTATIONS AFTER COVID-19 SINOPHARM VACCINATION

Main Article Content

Dr Noor Ul Huda Tunio
Dr Farah Khan
Dr Fahad Fehmi
Dr Ifrah Faizan
Dr Khola Aijaz
Dr Khushboo Sarwar Jamali
Dr Nadia Hashmi

Keywords

Common gastric manifestations after covid-19 vaccination,COVID-19 vaccine side effects, Gastric symptoms post COVID vaccination,GI symptoms after COVID-19 vaccine, COVID vaccine gastrointestinal reactions, Post-vaccination gastric issues,COVID-19 vaccine stomach problems, Digestive side effects of COVID vaccine

Abstract

The COVID-19 pandemic has underscored the significance of vaccination in protecting individuals from the virus. With multiple vaccines available, this study focuses on the Sinopharm vaccine, evaluating its gastric effects on recipients in both the short and long term. Our research, based on a comprehensive analysis of participant data, reveals that the Sinopharm COVID-19 vaccine is associated with gastric discomfort, acidity, and dyspepsia-like side effects, primarily in the long term, approximately one year post-vaccination. Notably, these side effects were observed not only in the general population but also in healthcare workers who received the vaccine. The findings of this study emphasize the importance of ongoing follow-up and regular evaluations to assess the long-term implications of the Sinopharm vaccine on stomach health and overall well-being. The development of an algorithm to monitor and address stomach health responses following vaccination is crucial for effective management and prevention strategies. This research contributes to the growing body of knowledge on vaccine-related side effects, highlighting the need for continued surveillance and evaluation of vaccine safety to inform evidence-based public health decisions.

Abstract 40 | Pdf Downloads 5

References

1. WHO Coronavirus (COVID-19) Dashboard https://covid19.who.int/, [accessed 21 August, 2021].
2. Krammer F. SARS-CoV-2 vaccines in development. Nature. 2020;586:516–527. [DOI] [PubMed] [Google Scholar]
3. https://education.cfr.org/learn/learning-journey/development-topics-development/the-race-to-develop-covid-19-vaccines
4. https://pmc.ncbi.nlm.nih.gov/articles/PMC9863525/#B18-vaccines-11-00105, https://pmc.ncbi.nlm.nih.gov/articles/PMC9863525/#B19-vaccines-11-00105.
5. World Health Organization Evidence Assessment: Sinopharm/BBIBP COVID-19 Vaccines. [(accessed on 1 October 2022)]; Available online: https://cdn.who.int/media/docs/default- source/immunization/sage/2021/april/2_sage29apr2021_critical-evidence_sinopharm.pdf
6. https://pubmed.ncbi.nlm.nih.gov/34912426/
7. https://www.mdpi.com/2076-393X/11/1/44
8. https://en.wikipedia.org/wiki/Pfizer%E2%80%93BioNTech_COVID-19_vaccine
9. Evaluation of Sinopharm and Sinovac COVID 19 vaccination adverse effects in Karachi—a survey, noted general “gastrointestinal disturbances” without specifics. J Pharm Res Int
10. Pernicious anemia following COVID 19 vaccination: Two case reports—identified autoimmune atrophic gastritis post-second Sinopharm dose. PMCPubMed
11.Atrophic gastritis and pernicious anemia mechanisms and context. Wikipedia+1
12.Soltani H et al. Pernicious Anemia Following COVID 19 Vaccination: A Report of Two Cases. Int J Hematol Oncol Stem Cell Res. 2023;17(3):220–223. IJHOSCRPMCPubMed
13.“Side effects after COVID 19 vaccination: a comparison between the most common available vaccines in Iran.” PMC (Sinopharm data: nausea 1.1%, diarrhea 1.1%, abdominal pain 1.7%)
14.Atrophic gastritis, Wikipedia overview—mechanism of disease. Wikipedia