Bacteriological study of the bacteria isolated from alkaline urine in women and their susceptibility to antimicrobial agents
Main Article Content
Keywords
Alkaline urine, Urine pH
Abstract
According to the findings, the typical level of (alkaline urine) found in patients suffering from an infection of the urinary tract was 10.6 percent. It was significantly higher in women who were not pregnant compared to women who weren’t pregnant (62.5% vs. 37.5%) at a probability levelP =0.0001. Most patients were in the age category of less than 25 years. All of the patients showed evidence of positive bacterial growth, and E. coli was shown to be the most prevalent bacteria (22.5%, P 0.05). Additionally, 46.8% of these samples included urease-producing bacteria. (Gentamycin),(Nalidixic acid and Phosphomycin 0 percent), and fractionally resistant to (Ciprofloxacin 50 percent efficacy), and (Azithromycine 60 percent). The only antibiotic that was effective against all of the
bacterial samples was 100% for Amoxacillin .
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27. Mahdi, E. M., & Mustafa, M. A. (2022). Effect of different concentrations of extract of Urtica dioica and Cladosporium cladosporiodes on Tribolium castaneum or: Coleoptera after 24-48 hours of exposure in Samarra City/Iraq. HIV Nursing, 22(2), 3207-3210.
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29. Kadham, S. M., Mustafa, M. A., Abbass, N. K., & Karupusamy, S. (2022). IoT and artificial intelligence–based fuzzy-integral N-transform for sustainable groundwater management. Applied Geomatics, 1-8.
2. Alperin, M.; Burnett, L.; Lukacz, E. and Brubaker, L.(2019). The mysteries of menopause and urogynecologic health: clinical and scientific gaps. Menopause. 26(1):103-111.
3. Araujo da Silva, AR.; Marques, AF.;BiscaiadiBiase, C.; Zingg, W.; Dramowski, A.and Sharland, M.(2018). Interventions to prevent
urinary catheter-associated infections in children and neonates: a systematic review. JPediatrUrol. 14(6):556.e1-556.e9.
4. Burian, A.; Erdogan, Z.;Jandrisits, C.andZeitlinger, M. (2012). Impact of pH on activity of trimethoprim, fosfomycin, amikacin,
colistin and ertapenem in human urine.Pharmacology .90(5-6):281-7.
5. Carlini, C.R. and Ligabue-Braun,R.(2016).Ureases as multifunctional toxic proteins: A review.Toxicon .110:90-109.
6. CLSI. (2012) .Methods for Dilution Anti microbial susceptibility Tests for Bacteria that Grow Aerobically ; Approved standard-Ninth
Edition M07-A9. CLSI. Clinical and LaboratoryStandards Institute, wayne,PA. USA .32(2) : 1-88 .
7. Cunha, B.A.; Giuga, J. and Gerson, S.(2016) Predictors of ertapenem therapeutic efficacy in the treatment of urinary tract infections (UTIs) in hospitalized adults: the importance of renal insufficiency and urinary pH.Eurp.J. Clin.Microbiol. Infect. Dis. [Epub ahead of print]
8. Derek, G.; Waller, BSc. (HONS), DM, MBBS (HONS), FRCP, Anthony P.Sampson MA, PhD, FHEA, FBPhS. (2018 ) .in Medical
Pharmacology and Therapeutics (Fifth Edition).
9. Ditkoff, EL.; Theofanides, M.; Aisen, CM.;Kowalik, CG,; Cohn, JA.; Sui, W.; Rutman, M.; Adam, RA.; Dmochowski, RR. and Cooper, KL. (2018). Assessment of practices in screening and treating women with bacteriuria. Can J Urol. 25(5):9486-9496.
10. Ganzeboom, KMJ.; Uijen, AA.; Teunissen,DTAM.; Assendelft, WJJ.; Peters, HJG.;Hautvast, JLA. andVan Jaarsveld, CHM.(2018).Urine cultures and antibiotics for urinary tract infections in Dutch general practice. Prim Health Care Res Dev. 31;:1-8.
11. Kumar, S.;Dave, A.;Wolf, B. and Lerma, E.V.(2015).Urinary tract infections. Dis. Mon.61(2):45-59.
12. Long, B. and Koyfman, A.(2018). The Emergency Department Diagnosis and Management of Urinary Tract Infection. Emerg
Med Clin North Am. 36(4):685-710.
13. Loose, M.;Naber, K.G.;Shields, P.;Reinhart, H. and Wagenlehner, F.M.E.(2018). Urinary concentrations and antimicrobial activity of
tobramycin in healthy volunteers receiving a single oral dose of a novel formulation for improved absorption. Int. J. Antimirob.
Agents.51(3):422-426.
14. Mark,B. and Jardine, A.G.(2013).in Encyclopedia of Human Nutrition (Third Edition).
15. Michael, J. Bono and Wanda, C. Reygaert.(2021).Urinary tract infection. NCBI, StatPearls Publishing.
16. Michael, R. Clarkson; Ciara, N.Magee and Barry, M. Brenner . (2011).Pocket companion to Brenner and Rector"s the kidney.
ScienceDirect.Book.Eighth Edition.
17. O'Grady, MC.; Barry, L.; Corcoran, GD.;Hooton, C.; Sleator, RD. and Lucey, B.(2019).Empirical treatment of urinary tract infections: how rational are our guidelines? JAntimicrobChemother. 01;74(1):214-217.
18. Richards, KA.; Cesario, S.; Best, SL.; Deeren, SM.; Bushman, W.; and Safdar, N. (2019).Reflex urine culture testing in an ambulatory urology clinic: Implications for antibiotic stewardship in urology. Int J Urol. 26(1):69-74.
19. Robin, R. S. (2015).Urine pH and composition influence the potency of a human antimicrobial molecule during urinary tract infections. J. Biol. Chem.290: 15949–60.
20. Sakamoto, S.; Miyazawa, K.; Yasui, T.; Iguchi, T.; Fujita, M.; Nishimatsu, H.; Masaki, T.;Hasegawa, T.; Hibi, H.; Arakawa, T.; Ando, R.;
Kato, Y.; Ishito, N.; Yamaguchi, S.; Takazawa,R.; Tsujihata, M.; Taguchi, M.; Akakura, K.;Hata, A. and Ichikawa, T. (2019).Chronological
changes in epidemiological characteristics of lower urinary tract urolithiasis in Japan. Int J Urol.26(1):96-101.
21. So, W. ;Crandon, J.L. and Nicolau, D.P. (2015).Effects of Urine Matrix and pH on the Potency of Delafloxacin and Ciprofloxacin
against UrogenicEscherichia coli and Klebsiellapneumoniae. J. Urol. 194(2):563-70.
22. Szweda, H. and Jozwik, M. (2016).Urinary tract infections during pregnancy - an updated overview. Dev Peroid Med.20(4):263-272.
23. Tang, M.; Quanstrom, K.; Jin, C. and Suskind, AM. (2019).Recurrent Urinary Tract Infections are Associated With Frailty in Older
Adults. Urology. 123:24-27.
24. The European foundation for the Care of Newborn Infants (EFCNI).(2020).143/235/22619, certificate dated .
25. Yamaji, R.; Friedman, CR.; Rubin, J.; Suh, J.;Thys, E.; McDermott, P.; Hung-Fan, M.; and Riley, LW. (2018).A Population-Based
Surveillance Study of Shared Genotypes of Escherichia coli Isolates from Retail Meat and Suspected Cases of Urinary Tract
Infections. mSphere.15;3(4).
26. Yang, L.;Wang, K.;Li, H.;Denstedt, J.D. and Cadieux, P.A.(2014). The influence of urinary pH on antibiotic efficacy against bacterial
uropathogens. Urology.84(3):731-7.
27. Mahdi, E. M., & Mustafa, M. A. (2022). Effect of different concentrations of extract of Urtica dioica and Cladosporium cladosporiodes on Tribolium castaneum or: Coleoptera after 24-48 hours of exposure in Samarra City/Iraq. HIV Nursing, 22(2), 3207-3210.
28. Mustafa, M. A., Kadham, S. M., Abbass, N. K., Karupusamy, S., Jasim, H. Y., Alreda, B. A., ... & Ahmed, M. T. (2023). A novel fuzzy M-transform technique for sustainable ground water level prediction. Applied Geomatics, 1-7.
29. Kadham, S. M., Mustafa, M. A., Abbass, N. K., & Karupusamy, S. (2022). IoT and artificial intelligence–based fuzzy-integral N-transform for sustainable groundwater management. Applied Geomatics, 1-8.
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Published
Mar 13, 2023
Article Details
How to Cite
Anfall M. Jumaa, Malak F. Mahdi, & Othman S. Mutlek. (2023). Bacteriological study of the bacteria isolated from alkaline urine in women and their susceptibility to antimicrobial agents. Journal of Population Therapeutics and Clinical Pharmacology, 30(3), 361–366. https://doi.org/10.47750/jptcp.2023.30.03.037
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