Study of the enzymatic antioxidants and trace elements level in the people infected by leishmaniasis

Main Article Content

Ohood Mozahim Shakir
Wasan Abdulmunem Taha
Sura Samir Muhammad

Keywords

leishmaniasis, Antioxidants, Trace elements

Abstract

Leishmaniasis is a protozoa parasite, unicellular, obligatory intracellular parasitism, bi-host; it has two phases in his life cycle the first phase it called Promastigote that live in the intestines of female sandflies belonging to genus. The second stage Amastigote grows and multiplies inside the macrophages of the vertebral storage host. The purpose of this study was to evaluate the effect of L. tropica on the antioxidants indicators and trace elements level. The current study included the collection of 55 serum samples from patients infected by the parasite L. tropica. The results showed a decrease(p < 0.05) in the concentration of glutathione, the level of zinc and iron, while it was noted that the concentration of peroxynitrite radical and the level of magnesium increased (p < 0.05) in patients by leishmaniasis compared to the control. The information gathered can be used to lessen the effect of L. tropica on human, by treating patients with cutting-edge methods.

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