DISCERNMENT OF ANTIMICROBIAL RESISTANCE AMONG HEALTH PROFESSIONALS AT A MEDICAL COLLEGE IN KOZHIKODE DISTRICT, INDIA - A QUALITATIVE STUDY
Main Article Content
Keywords
Antimicrobial resistance, Antibiotic stewardship, Healthcare professionals, Qualitative study
Abstract
Context: Overuse and misuse of antibiotics are imparting factors to the rising global public health epidemic known as antimicrobial resistance (AMR).
Aims: To determine the stumbling block to antimicrobial stewardship procedures and to yield methods for reducing antimicrobial resistance (AMR) in the organization.
Settings and Design:A teriary medical college hospital in Northern Kerala,India and Cross scetional study
Methods and Material: Key informant interviews were condcuted among expert practitioners from the Department of Internal Medicine,Pharmacology and and Microbiology from a tertiary medical college in Kozhikode, Kerala.
Statistical analysis used:The data were transcribed and subjected to thematic analysis.
Results: Two main themes emerged from the key
findings: (1) The factors affect antibiotic stewardship: pharmacokinetic problems, overuse, lack of surveillance, and environmental contamination; and (2) solutions to improve stewardship programs, emphasizing tactics like clinical audits, surveillance programs and utilizing advanced molecular diagnostics.
Conclusions: Combating AMR necessitates a multifaceted strategy that includes better surveillance systems, appropriate diagnostic use and improved antibiotic stewardship. AMR can be considerably reduced by institutional commitment to education and policy changes.
References
2. Collignon P, Laxminarayan R, Darling J, et al. Resistance to antibiotics: a global threat. Lancet Infect Dis. 2018;18(3):246-248.
3. Van Boeckel TP, Gandra S, Ashok A, et al. Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. Lancet Infect Dis. 2014;14(8):742-750.
4. Indian Council of Medical Research. Antimicrobial Resistance Surveillance Network. Available from: https://www.icmr.nic.in/content/antimicrobial-resistance-surveillance-network.
5. Klein EY, Van Boeckel TP, Martinez EM, et al. Global increase and geographic convergence in antibiotic consumption between 2000 and 2015. Proc Natl Acad Sci USA. 2020;117(14):7701-7710.
6. Laxminarayan R, Chaudhury RR. Antibiotic resistance in India: drivers and opportunities for action. BMJ. 2016;353:i2392.
7. National Centre for Disease Control. National Action Plan on Antimicrobial Resistance, India; 2017.
8. One Health Initiative. Available from: https://www.onehealthinitiative.com/.
9. Chokshi A, Sifri Z, Cennimo D, Horng H. Global contributors to antibiotic resistance. J Glob Infect Dis. 2019;11(1):36-42.
10. Dadgostar P. Antimicrobial Resistance: Implications and Costs. Infect Drug Resist. 2019;12:3903-3910.
11. Harbarth S, Dettenkofer M, Allegranzi B. Interventions to prevent and control methicillin-resistant Staphylococcus aureus: an overview. J Hosp Infect. 2007;65 Suppl 2:S161-72.
12. Barlam TF, Cosgrove SE, Abbo LM, et al. Implementing an antibiotic stewardship program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Clin Infect Dis. 2016;62(10):e51-e77.
13. Huttner B, Goossens H, Harbarth S. Antimicrobial stewardship: more than a program. Clin Microbiol Infect. 2015;21(4):322-9.
14. World Health Organization. Global Antimicrobial Resistance Surveillance System (GLASS) Manual. Geneva: WHO; 2015.
15. Livermore DM. Has the time come to curtail antibiotic use? Int J Antimicrob Agents. 2012;40 Suppl:S3-12.
