ASSOCIATION OF DIABETES MELLITUS WITH ABO BLOOD GROUP IN THE POPULATION IN AND AROUND DIBRUGARH
Main Article Content
Keywords
Diabetes mellitus type2, ABO blood groups, Association
Abstract
Background:-Diabetes mellitus an emerging global epidemic, is a multifactorial syndrome having a strong genetic connection.ABO blood group antigen which is a genetically determined variable also plays a important role in understanding inheritance pattern and disease susceptibility.The previous studies reported that there are various associations between particular ABO phenotypes and an increased susceptibility to disease. The rationale behind this study was that there might be an association between the ABO blood group and diabetes mellitus and based on result we can identify the susceptible and adopt some preventive measures to decrease the burden of disease in society.
Materials and method:-499 individuals were recruited in the study.Out of which 249 were diabetic individual and 250 were control.
Result;-Using blood group O as reference the odds ratio was calculated to see the association of different ABO blood group with diabetes mellitus .It was found that Blood group B showed a five times increase risk for development of diabetes mellitus.
Conclusion:-The present study shows a significant relationship between blood group B and type 2 diabetes mellitus
References
2. Ekoe, J.M., Zimmet, P. and Williams, R.: The epidemiology of Diabetes Mellitus: An International Perspective. John Wiley, Chichester (2001)
3. 3. Elbein, S.C., Craig, R. and Wang, H.: Association ofSMPs in Tandem Genes SCAMP3 and CLK2:Positional and functional candidates for type 2diabetes (T2DM). Abstract Book, 65th ScientificSessions. Organized by A Journal of the American Diabetes Association, California, pp. A286 (2005).
4. Guleria, K., Singh, H.P., Kaur, H. and Sambyal, V.: ABOblood groups in gastrointestinal tract (GIT) andbreast carcinoma patients. Anthropologist, 7: 189-192 (2005).
5. Huston AM, Atmar RL, Graham DY, Estes MK. Norwalk virus infection and disease is associated with ABO histo-blood group type. J Infect Dis 2002;185:1335-7.
6. Qureshi MA, Bhatti R. Frequency of blood groups among the diabetes mellitus type 2 patients. J Coll Physicians Surg Pak 2003;13:453-5.
7. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2014;37(Suppl 1):S81-90.
8. Meo SA1, Rouq FA, Suraya F, Zaidi SZ. Association of ABO and Rh blood groups with type 2 diabetes mellitus. Eur Rev Med Pharmacol Sci. 2016;20(2):237-42.
9. Qureshi et al, Frequency of ABO blood groups among the diabetes mellitus type 2 patients. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP [2003, 13(8):453455]
10. Muhammad Kamil, Hamid Ali Nagi Al-Jamal and Narazah Mohd Yusoff Association of ABO blood groups with diabetes mellitus Universiti Sains Malaysia, Penang, Malaysia Published. 2010; 5: 48-47
11. Fagherazzi G, Gusto G, Clavel-Chapelon F, Balkau B, Bonnet F. ABO and Rhesus blood groups and risk of type 2 diabetes: evidence from the large E3N cohort study. Diabetologia. 2015; 58(3):519-22
12. 17. Waseem Abdul Ghani, Iqbal Muhammad, Awwabkhan Omar, Tahir Muhammad Association of Diabetes Mellitus with ABO and Rh Blood groups. Pakistan. 2012; 8(2): 134 – 136. 18.
13. Jassim WE. Association of ABO blood group in Iraqis with hypercholesterolemia, hypertension and diabetes mellitus. East Mediterr Health J. 2012; 18: 888 ‑ 91. 19.
14. Kanazawa Y, Furusho T, Nakajima H,Amemiya S,Akanuma Y, Kosaka K. Blood groups and diabetes mellitus A possible tool in the analysis of the hereditary background of diabetes mellitus. Tohoku J Exp Med. 1983; 141 (l): 295‑9.
15. Moinzadeh F, Mahdieh Najafabady G, Toghiani A. Type 2 diabetes mellitus and ABO/Rh blood groups. J Res Med Sci. 2014; 19(4): 382.