INVESTIGATING THE IMPACT OF VITAMIN D AND CALCIUM METABOLISM ON DENTAL CARIES

Main Article Content

Dr. Momina Khan
Dr. Zaheer Ahmed Soomro
Dr.Uzma Faryal
Dr. Rashid Iqbal
Dr. Muhammad Amin Sahito
Dr. Mobeen Ali

Keywords

Dental caries,vitamin D, calcium metabolism, oral health, tooth mineralization, enamelintegrity, dietary habits, sun exposure, parathyroid hormone.

Abstract

Background:Dental caries remains a widespread oral health problem, influenced by multiplefactors, including diet, oral hygiene, and fluoride exposure. Recent evidence suggests that vitaminD andcalcium metabolism may also play a significant role in the development and progression ofcaries. Vitamin D is essential for calcium absorption and tooth mineralization, while calciumcontributes to enamel strength. A deficiency in either nutrient may lead to weakened enamel,increasing susceptibility to decay.This study aimed to investigate the relationship between serumvitamin D and calcium levels and the presence of dental caries among individuals attending thedental outpatient department at Women Medical and Dental College, Abbottabad. The study alsoexplored the role of dietary habits, sun exposure, and oral hygiene practices in influencing dentalhealth.


Methods:A cross-sectional study was conducted over one year, from January 2023 to January2024, involving 87 participants. Each individual underwent an oral examination to assess dentalcaries using the Decayed, Missing, and Filled Teeth (DMFT) Index. Blood samples were collectedto measure serum vitamin D, calcium, phosphorus, and parathyroid hormone (PTH) levels. Dietaryhabits, oral hygiene routines, and sunlight exposure were recorded through a structuredquestionnaire. Statistical analysis was performed to determine associations between biochemicalmarkers and dental caries, with a p-value of <0.05 considered statistically significant.


Results:The findings showed a‘significant association between low vitamin D levels and anincreased prevalence of dental caries (p = 0.001)’. Participants with lower serum calcium levels alsohad a higher incidence of caries (p = 0.029). Additionally, individuals‘with limited sun exposureand poor dietary calcium intake were more likely to have lower vitamin D levels and higher DMFTscores’. Those who consumed dairy regularly and practiced good oral hygiene had better dentalhealth outcomes.


Conclusion:This study supports the role of vitamin D and calcium metabolism in maintainingdental health. Deficiencies in these nutrients were linked to a higher risk of dental caries,emphasizing the need for adequate vitamin D intake through diet and sun exposure. Public healthinitiatives promoting balanced nutrition, routine dental care, and lifestyle modifications may helpreduce the prevalence of caries and improve oral health outcomes.

Abstract 32 | PDF Downloads 3

References

1.Nireeksha N, Hegde MN, Shetty SS, Kumari SN.FOK l vitamin D receptor gene polymorphism and risk of dental caries: a case‐control study. International Journal of Dentistry.2022;2022(1):6601566.
2.Poza-Pascual A, Serna-Muñoz C, Pérez-Silva A, Martínez-Beneyto Y, Cabello I, Ortiz-Ruiz AJ. Effects of fluoride and calcium phosphate-based varnishes in children at high risk of toothdecay: A randomized clinical trial. International journal of environmental research and publichealth. 2021;18(19):10049.
3.El Shiekh MA, Hanafy RMH. Relationship between vitamin D status and caries experience in a group of Egyptian children: a cross-sectional study. BMC Oral Health. 2023;23(1):374.
4.Patil DJ. Clinical implications of vitamin D in oral diseases-A Review. J Pharm Res Int. 2021:103-10.
5.Indumathi K, Sibyl S. Vitamin D and its influence on oral health: A literature review. Research Journal of Pharmacy and Technology. 2023;16(5):2507-12.
6.Ali N, Yunus F, Siddique S, Tahir H. Role of Calcium in Development of Early Childhood Dental Caries. Pakistan Journal of Medical & Health Sciences. 2022;16(07):897-.
7.Li Z, Wei X, Shao Z, Liu H, Bai S. Correlation between vitamin D levels in serum and the risk of dental caries in children: a systematic review and meta-analysis. BMC oral health.2023;23(1):768.
8.Al-Jubori SH, Al-Murad MA, Al-Mashhadane FA. Effect of oral vitamin D3 on dental caries: an in-vivo and in-vitro study. Cureus. 2022;14(5).
9.Saboktakin L. The relationship between vitamin D and calcium serum levels with dental caries in 6-12 years old children. Journal of Parathyroid Disease. 2022;10(1):e9141-e.
10.Peponis M, Antoniadou M, Pappa E, Rahiotis C, Varzakas T. Vitamin D and Vitamin D Receptor Polymorphisms Relationship to Risk Level of Dental Caries. Applied Sciences.2023;13(10):6014.
11.Bumbu BA, Luca MM, Buzatu R. Examining the role of vitamin d in caries susceptibility in children’s deciduous teeth: a systematic review. Nutrients. 2023;15(22):4826.
12.Pratyusha N, Vinay C, Uloopi K, RojaRamya KS, Ahalya P, Devi C. Association of serum Vitamin D and salivary calcium and phosphorus levels in 3-11-year-old schoolchildren withdental caries. Journal of Indian Society of Pedodontics and Preventive Dentistry.2021;39(3):240-5.
13.Pu R, Fu M, Li N, Jiang Z. A certain protective effect of vitamin D against dental caries in US children and youth: A cross‐sectional study. Journal of public health dentistry. 2023;83(3):231-8.
14.Børsting T, Fagerhaug TN, Schuller A, van Dommelen P, Stafne SN, Mørkved S, et al. The association between serum vitamin D status and dental caries or molar incisorhypomineralisation in 7–9-year-old Norwegian children: a cross-sectional study. BMC PublicHealth. 2024;24(1):246.
15.Mahmood MK, Tassery H, Tardivo D, Lan R. Association between Vitamin D Levels and Dental Caries: a systematic review and dose-response Meta-analysis of cross-sectional studies.Applied Sciences. 2023;13(17):9883.
16.Hu Z, Zhou F, Xu H. Circulating vitamin C and D concentrations and risk of dental caries and periodontitis: A Mendelian randomization study. Journal of Clinical Periodontology.2022;49(4):335-44.
17.Ji S, Zhao K, Ma L, Chen X, Zheng D, Lu Y. The Association Between Vitamin D and Early Childhood Caries: A Systematic Review and Meta-Analysis. Oral Health & PreventiveDentistry. 2024;22:b4928565.
18.Beckett DM, Broadbent JM, Loch C, Mahoney EK, Drummond BK, Wheeler BJ. Dental consequences of Vitamin D deficiency during pregnancy and early infancy—an observationalstudy. International journal of environmental research andpublic health. 2022;19(4):1932.
19.Nascimento GG, Leite FR, Gonzalez-Chica DA, Peres KG, Peres MA. Dietary vitamin D and calcium and periodontitis: A population-based study. Frontiers in nutrition. 2022;9:1016763.
20.Swapna LA, Abdulsalam R. Vitamin D deficiency and its effects on tooth structure and pulpal changes. Open Access Macedonian Journal of Medical Sciences. 2021;9(F):81-7.
21.Suárez-Calleja C, Aza-Morera J, Iglesias-Cabo T, Tardón A. Vitamin D, pregnancy and caries in children in the INMA-Asturias birth cohort. BMC pediatrics. 2021;21:1-9.
22.Khawaja W, Shaweesh M. The impact of vitamin D deficiency on general and oral health during childhood. Scholars Journal of Dental Sciences. 2022;9:155-61.

Most read articles by the same author(s)