COMPARING INTRA-LESIONAL VERAPAMIL AND TRIAMCINOLONE ACETONIDE FOR KELOID TREATMENT
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Keywords
Keloid, Triamcinolone acetonide, Verapamil, Intralesional therapy, Scar management, Recurrence.
Abstract
Introduction: Keloids are painful, fibroproliferative scars, and the problems also have associated itching and cosmetic problems. Among the researched intralesional agents, we find triamcinolone acetonide (TAC) and verapamil where the findings are conflicting on the matter of the relative rates of efficacy.
Objective: The study aimed at assessing the effectiveness of intralesional verapamil and triamcinolone acetonide towards the treatment of keloid scar with regards to safety, rate of recurrence and tolerability of the two treatment systems to the patient.
Material and Methods: The type of research was randomized clinical trial and the research was carried out in the month of July, 2024 to December, 2024 at Dermatology Department, Rai Medical College Sargodha, Pakistan. Sample size consisted of 60 patients. Group A: verapamil was administered and Group B: TAC was administered. The use of Vancouver Scar Scale determined clinical response, adverse effects and the recurrence were recorded.
Results: The two agents were very effective in the amelioration of scar characteristics. Faster initial response and more adverse effect were noted with TAC, and stabilized effects were noticed with less problems and mildly less recurrence with verapamil.
Conclusion: Keloids can be treated with the use of TAC and verapamil, verapamil is tolerable more than TAC.
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Naimat Ullah
Associate Professor of Dermatology, Bannu Medical College, Medical Teaching Institution (MTI) Bannu, Pakistan
Janaan Arfeen
Aesthetic and Antiagying Physician Australia, MBBS, FACAM, FACCSM, Fellow A4M (Aesthetic med), DABRM (USA), Board certified AAAM (Aust), M.Sc Aesthetic and Cosmetic Med(UK), Teaching faculty of Aesthetic Medicine USW-UK
Lubna Rani Faysal
Associate Professor, Department of Dermatology, Pakistan Railway Hospital, Islamic International Medical College, Riphah International University Islamabad, Pakistan
Asma Javed
Associate Professor of Dermatology, Foundation University School of Health Sciences, Dermatology Department, Fauji Foundation Hospital Rawalpindi/ FUSH, Pakistan
Javaria Rahmatullah
FCPS Dermatology, Post Graduate, JPMC, Pakistan
Seemal Akram
Assistant Professor, Rai Foundation Medical College Sargodha, Pakistan