AUTOPSY FINDINGS IN RELATION TO AGE AND GENDER: A CROSS-SECTIONAL STUDY
Main Article Content
Keywords
Autopsy, Age, Gender, Mortality, Forensic Medicine
Abstract
Objective: To evaluate autopsy findings in relation to age and gender.
Study design: Retrospective observational study
Duration and place of study: This study was conducted in Karachi Medical and Dental College Karachi from May 2024 to May 2025
Methodology: The study has 300 medicolegal autopsy cases which were examined in this retrospective and observational study. Data on demographical consideration, age, gender and the reason of deaths were read and classified. Descriptive statistics were used to evaluate trends that occur among different age groups and gender.
Results: Of 300 autopsies, 224 (74.7%) were of males and 76 (25.3%) were of females. Deaths were most prevalent among the aged group 3959 years (57.3%) followed by 1838 years (28.3%) and 60 or above (14.4%). The predominant cause of death was road traffic accidents which contributed to 69 cases (23.0%). These were followed by injuries with a firearm (57, 19.0%), asphyxial deaths (55, 18.3%), assaults (51, 17.0%), poisoning (29, 9.7%), and electrocution (24, 8.0 percent). The cause of death reported was unascertainable in 15 cases (5.0%). In every category, more men as compared to women were affected, especially in road traffic accidents, gunshots and assaults.
Conclusion: The results of autopsy revealed that middle-aged males are most affected with the leading causes being the road traffic accidents, death by gun, and asphyxial. These findings indicate the significance of age and gender to the interpretation of mortality trend and the ongoing relevance of autopsies to the forensics and clinical practices.
References
2. Sarode VR, Datta BN, Banerjee AK, et al. Autopsy findings and clinical diagnoses: a review of 1,000 cases. Hum Pathol. 1993;24(2):194–8.
3. Roosen J, Frans E, Wilmer A, Knockaert DC, Bobbaers H. Comparison of premortem clinical diagnoses in critically ill patients and subsequent autopsy findings. Mayo Clin Proc. 2000;75(6):562–7.
4. Stevanovic G, Tucakovic G, Dotlic R, Kanjuh V. Correlation of clinical diagnoses with autopsy findings: a retrospective study of 2,145 consecutive autopsies. Hum Pathol. 1986;17(12):1225–30.
5. Burton JL. The history of the autopsy. In: The Hospital Autopsy. CRC Press; 2010. p. 1–10.
6. Marshall HS, Milikowski C. Comparison of clinical diagnoses and autopsy findings: six-year retrospective study. Arch Pathol Lab Med. 2017;141(9):1262–6.
7. Nashelsky MB, Lawrence CH. Accuracy of cause of death determination without forensic autopsy examination. Am J Forensic Med Pathol. 2003;24(4):313–9.
8. Pomara C, Fineschi V, Scalzo G, Guglielmi G. Virtopsy versus digital autopsy: virtuous autopsy. Radiol Med. 2009;114(8):1367–79.
9. Wong PW, Chan WS, Chen EY, et al. Suicide among adults aged 30–49: a psychological autopsy study in Hong Kong. BMC Public Health. 2008;8(1):147.
10. Appleby L, Cooper J, Amos T, Faragher B. Psychological autopsy study of suicides by people aged under 35. Br J Psychiatry. 1999;175(2):168–74.
11. Yang GH, Phillips MR, Zhou MG, et al. Understanding the unique characteristics of suicide in China: national psychological autopsy study. Biomed Environ Sci. 2005;18(6):379–89.
12. Azmak D. Asphyxial deaths: a retrospective study and review of the literature. Am J Forensic Med Pathol. 2006;27(2):134–44.
13. Dozono K, Ishii N, Nishihara Y, Horie A. An autopsy study of the incidence of lacunes in relation to age, hypertension, and arteriosclerosis. Stroke. 1991;22(8):993–6.
14. Pirisi M, Avellini C, Fabris C, et al. Portal vein thrombosis in hepatocellular carcinoma: age and sex distribution in an autopsy study. J Cancer Res Clin Oncol. 1998;124(7):397–400.
15. Spiliopoulou C, Papadodima S, Kotakidis N, Koutselinis A. Clinical diagnoses and autopsy findings: a retrospective analysis of 252 cases in Greece. Arch Pathol Lab Med. 2005;129(2):210–4.
16. Coradazzi AL, Morganti ALC, Montenegro MRG. Discrepancies between clinical diagnoses and autopsy findings. Braz J Med Biol Res. 2003;36(3):385–91.
17. Pastores SM, Dulu A, Voigt L, et al. Premortem clinical diagnoses and postmortem autopsy findings: discrepancies in critically ill cancer patients. Crit Care. 2007;11(2):R48.
18. Arafat SY, Mohit MA, Mullick MS, et al. Risk factors for suicide in Bangladesh: case–control psychological autopsy study. BJPsych Open. 2021;7(1):e17.
19. Conwell Y, Duberstein PR, Cox C, et al. Relationship of age and Axis I diagnoses in victims of completed suicide: a psychological autopsy study. Am J Psychiatry. 1996;153(8):1001–8.
20. Foster T, Gillespie K, McLelland R, Patterson C. Risk factors for suicide independent of DSM–III–R Axis I disorder: Case–control psychological autopsy study in Northern Ireland. Br J Psychiatry. 1999;175(2):175–9.
21. Suominen K, Isometsä E, Heilä H, Lönnqvist J, Henriksson M. General hospital suicides: a psychological autopsy study in Finland. Gen Hosp Psychiatry. 2002;24(6):412–6.
22. Chen EY, Chan WS, Wong PW, et al. Suicide in Hong Kong: a case-control psychological autopsy study. Psychol Med. 2006;36(6):815–25.
23. Azmak D. Asphyxial deaths: a retrospective study and review of the literature. Am J Forensic Med Pathol. 2006;27(2):134–44.
24. Roosen J, Frans E, Wilmer A, Knockaert DC, Bobbaers H. Comparison of premortem clinical diagnoses in critically ill patients and subsequent autopsy findings. Mayo Clin Proc. 2000;75(6):562–7.
25. Spiliopoulou C, Papadodima S, Kotakidis N, Koutselinis A. Clinical diagnoses and autopsy findings: a retrospective analysis of 252 cases in Greece. Arch Pathol Lab Med. 2005;129(2):210–4.
26. Coradazzi AL, Morganti ALC, Montenegro MRG. Discrepancies between clinical diagnoses and autopsy findings. Braz J Med Biol Res. 2003;36(3):385–91.
27. Yang GH, Phillips MR, Zhou MG, Wang LJ, Zhang Y, Xu D. Understanding the unique characteristics of suicide in China: national psychological autopsy study. Biomed Environ Sci. 2005;18(6):379–89.
28. Arafat SY, Mohit MA, Mullick MS, Kabir R, Khan MM. Risk factors for suicide in Bangladesh: case–control psychological autopsy study. BJPsych Open. 2021;7(1):e17.
29. Pastores SM, Dulu A, Voigt L, Raoof N, Alicea M, Halpern NA. Premortem clinical diagnoses and postmortem autopsy findings: discrepancies in critically ill cancer patients. Crit Care. 2007;11(2):R48.