COMPARISON OF PORTAL AND RENAL DOPPLER PARAMETERS IN PATIENTS OF CHRONIC LIVER DISEASE WITH OR WITHOUT AKI
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Keywords
Chronic liver disease (CLD), Acute kidney injury (AKI), Hepatorenal syndrome (HRS), Portal Vein (PV), Hepatic artery (HA), Resistive index (RI), Peak systolic velocity (PSV)
Abstract
Aim: To compare portal & renal doppler parameters in patients with AKI vs non-AKI in chronic liver disease patients.
Methods: This prospective study was conducted over two years at MM Institute of Medical Sciences, Mullana, Ambala, and included 100 patients diagnosed with CLD. Patients were classified according to the Child-Pugh score and assessed for the presence of AKI using KDIGO criteria. Portal vein peak systolic velocity (PSV), hepatic artery resistive index (RI), and renal RI were measured using duplex Doppler ultrasonography.
Results: Among the study population, alcohol-related liver disease was the most common etiology (58%). Decompensated cirrhosis was observed in 56% of patients. AKI was present in 33% of cases, and HRS was diagnosed in 8%, exclusively among those with decompensated cirrhosis. Doppler findings showed a significantly reduced portal vein PSV and elevated hepatic artery RI in decompensated patients (p < 0.05). Renal RI was significantly higher in patients with AKI compared to those without (p = 0.033), with the highest values seen in HRS cases.
Conclusion: Portal and renal Doppler ultrasonography provides a valuable, non-invasive method for assessing hepatic and renal hemodynamics in CLD patients. Doppler parameters correlate with disease severity and renal impairment, particularly in detecting AKI and HRS. Routine use of Doppler imaging may enhance early diagnosis, risk stratification, and clinical management in chronic liver disease.
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Dr. Ayushi
Senior Resident, Department of Gastroenterology, MMIMSR, Mullana
Dr. Vivek Ahuja
Professor, Department of Gastroenterology, MMIMSR, Mullana
Dr. Madhur Sharma
Senior Resident, Department of Gastroenterology, MMIMSR, Mullana
Dr. Amit Shrivastava
Assistant Professor, Department of Radiodiagnosis, MMIMSR, Mullana
Dr. Sudhir Mehta
Associate Professor, Department of Nephrology, MMIMSR, Mullana