PULMONARY MANIFESTATIONS IN A CASE OF SECONDARY SJOGRENS SYNDROME WITH COMORBIDITIES
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Abstract
Sjogrens syndrome is a chronic, multisystem autoimmune disease, characterized by lymphocytic infiltration of exocrine glands and other non-exocrine glands, affecting epithelium of salivary glands and lacrimal glands. The disease has female predominance, in 4th or 5th decade of life. It is 2nd most common autoimmune disease after rheumatoid arthritis, characterized by xerostomia and xerophthamia. Sjogrens syndrome is classified as primary Sjogrens syndrome or secondary Sjogrens syndrome in addition to other autoimmune disease such as rheumatoid arthritis. The diagnosis is made by checking for ocular and oral symptoms, Schrimers test, minor salivary gland biopsy, sialometry, presence of antibodies in serum.
Lung involvement affects patient’s quality of life. It has great impact on the overall prognosis and frequently leads to change in the treatment plans, thereby highlighting the importance of maintaining a high index of clinical suspicion and by taking appropriate steps to facilitate early diagnosis and intervention. A multidisciplinary approach involving rheumatologists, pulmonologists, and other specialists is recommended.
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Dr Avinash Kumar
M.S. Associate Professor, Dept. of Otorhinolaryngology – Head and Neck Surgery Saraswathi Institute of Medical Sciences (SIMS) Anwarpur ,Hapur, U.P.
Dr Mansi Sharma
M.S. Assistant Professor, Dept. of Otorhinolaryngology – Head and Neck Surgery Saraswathi Institute of Medical Sciences (SIMS) Anwarpur ,Hapur, U.P.
Dr Garima Sinha
Assistant Professor, Dept. of Anaesthesia and Critical Care, Government Institute of Medical Sciences ( GIMS ) Greater Noida , U.P.
Vidushi Singh
Fourth Year MBBS student Noida International Institute of Medical Sciences, Greater Noida, U.P.