BACTERIOLOGICAL PROFILE OF DIABETIC FOOT ULCER IN A TERTIARY CARE HOSPITAL
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Abstract
Diabetic foot ulcer (DFU) is one the most serious complication of Diabetes mellitus and leading cause of hospitalization and increase expenditure in health care system. Bacteriological profile and antibiotic susceptibility pattern to microbes in DFU has been undergoing changes over period of time. Pus, exudate from base of diabetic foot ulcer were taken after cleaning the area with saline gauge. Bacterial identification and sensitivity patterns were done by VITEK 2 Compat system. Maximum cases were seen in the age group between 46–65 years and males were affected more. Pseudomonas aeruginosa was the most common organism isolated ( 24.54%) followed by Methicillin resistant staphylococcus aureus ( MRSA) (16.36%) , Escherichia coli(12.72%), klebsiella pneumoniae( 10.90%) Enterococcus species ( 7.27%), Acinetobacter species( 5.45%), Proteus mirabilis ( 4.54%) , Enterobacter cloacae ( 4.54%) ,Methicillin sensitive staphylococcus aureus(4.54%), Enterobacter aerogenes(3.63%) Methicillin resistant coagulase negative staphylococcus(03.63%), and Morganella species (1.81%).All staphylococcus aureus were sensitive to vancomycin and linezolid. All the gram-negative bacilli showed highest sensitivity to piperacillin tazobactam, meropenem and imipenem overall. Least sensitivity by all gram-negative organisms were shown to ciprofloxacin
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Dr Athira Jayaram
ssistant Professor Department of Microbiology MVJMC & RH, Bangalore ORCID ID-0000-0001-7781-4190
Dr Priyanka Narayankar
Assistant Professor Department of Microbiology MVJMC & RH, Bangalore ORCID ID-0009-0008-2668-1541
Dr Khushboo Sareen
Assistant Professor Department of Microbiology VIMS Medical college, UP ORCID ID-0000-0002-7222-5458